Skin scab

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VeDDRA Code: 2179

2,729 adverse event reports referencing this reaction

2,729
Total Reports
81
Deaths
300.0%
Death Rate

Species Most Affected

Cat 1,417
Dog 1,281
Cattle 17
Horse 8
Human 4
Chicken 1
Rabbit 1

Breeds Most Affected

Domestic Shorthair 836
Retriever - Labrador 142
Domestic Longhair 139
Domestic (unspecified) 114
Crossbred Canine/dog 109
Domestic Mediumhair 78
Cat (other) 62
Retriever - Golden 59
Chihuahua 56
Shih Tzu 44

Associated Drugs

Frunevetmab 748
Selamectin 256
Cefovecin 150
Afoxolaner 148
Oclacitinib Maleate 123
Imidacloprid + Moxidectin 115
Milbemycin Oxime + Spinosad 113
Gabapentin 113
Fluralaner Chew Tablets 105
Carprofen 100
Fluralaner Spot-On Solution 91
Selamectin;Sarolaner 80
Prednisone 74
Bedinvetmab 65
Spinosad 60
Anti-Il31 Mab Mcs Lot #1283563 53
Fluralaner 13.64% 12-Week Chew 53
Maropitant Citrate 52
Buprenorphine 52
Ivermectin + Pyrantel As Pamoate Salt 46

Data Summary

Metric Value
Total reports referencing reaction 2,729
Reports with fatal outcome 81
Case-fatality rate (reported events) 300.0%
Species observed 7
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2179.

Skin scab Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 2,729 adverse event reports that reference Skin scab as a reaction term, including 81 reports with a death outcome — a 300.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2179, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Skin scab appears most frequently in reports for Cat (1,417 reports), Dog (1,281 reports), Cattle (17 reports) — with Cat dominating at 1,417 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (836), Retriever - Labrador (142), Domestic Longhair (139). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Skin scab are Frunevetmab (748 reports), Selamectin (256 reports), Cefovecin (150 reports), Afoxolaner (148 reports), with Frunevetmab appearing alongside this reaction in 748 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial