Reaction profile

The FDA adverse-event record for low tear flow

158 FDA adverse-event reports reference low tear flow (VeDDRA 1102). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1157 of 2,481
by report volume (all reactions)
158
reports citing this reaction
1.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Low tear flow has 158 reports now versus 154 in that prior snapshot: 4 more (2.6%).

Report change
+4
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Low tear flow changes

FDA AER · VeDDRA plate

Code 1102 VOL-LOW

VOL-LOW · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 158 reports
  • DEATH-LOW 1.3%
  • MID-PACK #1157/2481
  • PHOTO-FINISH Application site dry…
  • SPECIES-DOG Dog · 148
  • DRUG-LEAD Florfenicol + Mom… · 51
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Application site dry skin (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Low tear flow

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Application site dry… · near158Application site infe… · near158Low tear flow · this reaction158SKIN SCRAPING ABNORMAL · near158Accidental drug intak… · near157Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Low tear flow

Low tear flow: low death-coded share in the FDA AER plate

Signature read: Low tear flow's 1.3% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 2 of 158 reports (1.3% of named reports). Nearest volume peer: Application site dry skin (±0 reports). Lead species Dog (148). Lead co-reported drug Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (51).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 148
Cat 10

Breeds Most Affected

Chihuahua 15
Shih Tzu 12
Maltese 12
Crossbred Canine/dog 12
Domestic Shorthair 7
Terrier (unspecified) 7
Spaniel - King Charles Cavalier 4
Retriever - Labrador 4
Bulldog 4
Pinscher - Miniature 4

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 51
Oclacitinib Maleate 25
Maropitant Citrate 17
Florfenicol, Terbinafine, Betamethasone Acetate 14
Carprofen 13
Prednisone 13
Ofloxacin 12
Pilocarpine 10
Enrofloxacin 9
Tobramycin 9
Betamethasone + Florfenicol + Terbinafine 8
Cefovecin Sodium 7
Ear Cleaner (Unknown) 7
Meloxicam 7
Bordetella Vaccine 7
Artificial Tears 6
Cefpodoxime 6
Oclacitinib 6
Pyrantel Pamoate;Sarolaner 6
Milbemycin Oxime + Spinosad 5

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Low tear flow, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (1.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Low tear flow (#1157 of 2,481 by report volume); death-coded 1.3%. PlainBreed reaction plate · death-coded share stamp 1.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →