Reaction profile

The FDA adverse-event record for elevated fibrinogen level

72 FDA adverse-event reports reference elevated fibrinogen level (VeDDRA 2268). See the species, breeds, and drugs most associated with it below.

72
reports citing this reaction
31.9%
death-coded share
Horse
most-affected species
Polysulfated Glycosaminoglycan
most-associated drug
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72
Total Reports
23
Deaths
31.9%
Death Rate

Species Most Affected

Horse 42
Dog 27
Monkey 1
Cattle 1
Goat 1

Breeds Most Affected

Thoroughbred 11
Quarter Horse 9
Horse (other) 4
Retriever - Golden 4
Warmblood (unspecified) 4
Crossbred Canine/dog 3
Retriever - Labrador 3
Arab 3
Shih Tzu 3
Unknown 2

Associated Drugs

Polysulfated Glycosaminoglycan 13
Clodronate Disodium 8
Carprofen 7
Firocoxib 6
Ceftiofur 5
Flunixin Meglumine 5
Maropitant Citrate 4
Ceftiofur Crystalline Free Acid 4
Meloxicam 4
Moxidectin 4
Flunixin 3
Oxytetracycline 3
Gabapentin 3
Prednisone 3
Metronidazole 3
Pyrantel Pamoate 3
Detomidine 2
Dexmedetomidine Hydrochloride 2
Pergolide Mesylate 2
Fluralaner Chew Tablets 2

Elevated fibrinogen level Reaction Insights

72 reports name Elevated fibrinogen level; 23 recorded a death outcome (31.9% of reported events, not a population-level mortality rate). VeDDRA code: 2268.

By species: Horse (42 reports), Dog (27 reports), Monkey (1 reports). By breed: Thoroughbred (11), Quarter Horse (9), Horse (other) (4).

Most co-reported drugs: Polysulfated Glycosaminoglycan (13 reports), Clodronate Disodium (8 reports), Carprofen (7 reports), Firocoxib (6 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.