Reaction profile

The FDA adverse-event record for haemoglobinuria

75 FDA adverse-event reports reference haemoglobinuria (VeDDRA 2027). See the species, breeds, and drugs most associated with it below.

75
reports citing this reaction
30.7%
death-coded share
Dog
most-affected species
Maropitant Citrate
most-associated drug
Verify with FDA CVM →
75
Total Reports
23
Deaths
30.7%
Death Rate

Species Most Affected

Dog 64
Cat 7
Horse 2
Cattle 2

Breeds Most Affected

Retriever - Labrador 8
Domestic Shorthair 6
Crossbred Canine/dog 5
Shepherd Dog - German 4
Terrier - Yorkshire 3
Rottweiler 2
Terrier - Boston 2
Quarter Horse 2
Siberian Husky 2
Spaniel - Cocker American 2

Associated Drugs

Maropitant Citrate 12
Doxycycline 8
Carprofen 7
Famotidine 6
Gabapentin 6
Moxidectin 5
Prednisone 5
Spinosad 4
Melarsomine Dihydrochloride 4
Firocoxib 4
Cefovecin 4
Fluralaner Chew Tablets 4
Dexamethasone Sodium Phosphate 4
Suanovil 50 4
Bedinvetmab 4
Sucralfate 3
Milbemycin Oxime + Spinosad 3
Rabies Vaccine 3
Deracoxib 3
Diphenhydramine Hcl 3

Haemoglobinuria Reaction Insights

75 reports name Haemoglobinuria; 23 recorded a death outcome (30.7% of reported events, not a population-level mortality rate). VeDDRA code: 2027.

By species: Dog (64 reports), Cat (7 reports), Horse (2 reports). By breed: Retriever - Labrador (8), Domestic Shorthair (6), Crossbred Canine/dog (5).

Most co-reported drugs: Maropitant Citrate (12 reports), Doxycycline (8 reports), Carprofen (7 reports), Famotidine (6 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.