Food allergy

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VeDDRA Code: 1481

201 adverse event reports referencing this reaction

201
Total Reports
2
Deaths
100.0%
Death Rate

Species Most Affected

Dog 195
Cat 5
Unknown 1

Breeds Most Affected

Dog (unknown) 32
Retriever - Labrador 20
Shih Tzu 10
Pit Bull 10
Chihuahua 9
Crossbred Canine/dog 8
Shepherd Dog - German 8
Bulldog 7
Terrier - Yorkshire 6
Boxer (German Boxer) 6

Associated Drugs

Milbemycin Oxime + Spinosad 76
Milbemycin Oxime + Praziquantel 51
Ivermectin + Pyrantel As Pamoate Salt 27
Spinosad 13
Milbemycin Oxime 10
Afoxolaner 10
Lotilaner 8
Prednisone 6
Grapiprant 6
Cyclosporine 5
Enrofloxacin 4
Oclacitinib Maleate 4
Ivermectin 3
Trilostane 3
Milbemycin/Lufenuron Tablets 3
Fluralaner 13.64% 12-Week Chew 3
Imidacloprid + Moxidectin 3
Phenylpropropanolamine Hcl 3
Hypoallergenic Diet (Unknown) 2
Ivermectin/Pyrantel Pamoate Chewable 68Mcg/163Mg 2

Data Summary

Metric Value
Total reports referencing reaction 201
Reports with fatal outcome 2
Case-fatality rate (reported events) 100.0%
Species observed 3
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1481.

Food allergy Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 201 adverse event reports that reference Food allergy as a reaction term, including 2 reports with a death outcome — a 100.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1481, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Food allergy appears most frequently in reports for Dog (195 reports), Cat (5 reports), Unknown (1 reports) — with Dog dominating at 195 entries. Within those species, the breeds most often named alongside this reaction are Dog (unknown) (32), Retriever - Labrador (20), Shih Tzu (10). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Food allergy are Milbemycin Oxime + Spinosad (76 reports), Milbemycin Oxime + Praziquantel (51 reports), Ivermectin + Pyrantel As Pamoate Salt (27 reports), Spinosad (13 reports), with Milbemycin Oxime + Spinosad appearing alongside this reaction in 76 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial