Reaction profile

The FDA adverse-event record for food allergy

201 FDA adverse-event reports reference food allergy (VeDDRA 1481). See the species, breeds, and drugs most associated with it below.

201
reports citing this reaction
1.0%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
201
Total Reports
2
Deaths
1.0%
Death Rate

Species Most Affected

Dog 195
Cat 5
Unknown 1

Breeds Most Affected

Dog (unknown) 32
Retriever - Labrador 20
Shih Tzu 10
Pit Bull 10
Chihuahua 9
Crossbred Canine/dog 8
Shepherd Dog - German 8
Bulldog 7
Terrier - Yorkshire 6
Boxer (German Boxer) 6

Associated Drugs

Milbemycin Oxime + Spinosad 76
Milbemycin Oxime + Praziquantel 51
Ivermectin + Pyrantel As Pamoate Salt 27
Spinosad 13
Milbemycin Oxime 10
Afoxolaner 10
Lotilaner 8
Prednisone 6
Grapiprant 6
Cyclosporine 5
Enrofloxacin 4
Oclacitinib Maleate 4
Ivermectin 3
Trilostane 3
Milbemycin/Lufenuron Tablets 3
Fluralaner 13.64% 12-Week Chew 3
Imidacloprid + Moxidectin 3
Phenylpropropanolamine Hcl 3
Hypoallergenic Diet (Unknown) 2
Ivermectin/Pyrantel Pamoate Chewable 68Mcg/163Mg 2

Food allergy Reaction Insights

201 reports name Food allergy; 2 recorded a death outcome (1.0% of reported events, not a population-level mortality rate). VeDDRA code: 1481.

By species: Dog (195 reports), Cat (5 reports), Unknown (1 reports). By breed: Dog (unknown) (32), Retriever - Labrador (20), Shih Tzu (10).

Most co-reported drugs: Milbemycin Oxime + Spinosad (76 reports), Milbemycin Oxime + Praziquantel (51 reports), Ivermectin + Pyrantel As Pamoate Salt (27 reports), Spinosad (13 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.