Reaction profile

The FDA adverse-event record for persistent cough

18 FDA reports name persistent cough, a lower-volume reaction in the CVM extract (VeDDRA 2875). Plate stamps and neighbourhood peers follow.

#2224 of 2,481
by report volume (all reactions)
18
reports citing this reaction
22.2%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Persistent cough has 18 reports now versus 18 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Persistent cough changes

FDA AER · VeDDRA plate

Code 2875 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 18 reports
  • DEATH-HOT 22.2%
  • LOWER-Q #2224/2481
  • PHOTO-FINISH ALBUMIN/GLOBULIN RATI…
  • SPECIES-DOG Dog · 15
  • DRUG-LEAD Oclacitinib Malea… · 7
  • DESK-WIDE 16 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: ALBUMIN/GLOBULIN RATIO HI, BLD (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Persistent cough

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348ALBUMIN/GLOBULIN RATI… · near18Application site skin… · near18Bone marrow hypoplasia · near18Cognitive disturbance · near18Persistent cough · this reac…18Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Persistent cough

What the FDA AER plate says about Persistent cough

Signature read: 18 reports place Persistent cough in the lower third of FDA AER volume (#2224 of 2,481). Report volume is lower-third scale: 18 named reports in the openFDA extract. 4 of 18 reports were death-coded (22.2% of named reports, not a population mortality rate). Nearest volume peer: ALBUMIN/GLOBULIN RATIO HI, BLD (±0 reports). Lead species Dog (15). Lead co-reported drug Oclacitinib Maleate (7).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Oclacitinib Maleate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 15
Cat 2
Human 1

Breeds Most Affected

Terrier - Bull - American Pit 2
Terrier - Yorkshire 2
Domestic Longhair 1
Mastiff 1
Unknown 1
Shih Tzu 1
Domestic Shorthair 1
Boxer (German Boxer) 1
Chihuahua 1
Pit Bull 1

Associated Drugs

Oclacitinib Maleate 7
Bedinvetmab 5
Moxidectin 2
Sarolaner 2
Ketoconazole 2
Ear Ointment (Unknown) 2
Midazolam 2
Phenobarbital 2
Laser Therapy 2
Ketamine 2
Lactated Ringer&Apos;S Solution 2
Selamectin;Sarolaner 1
Unknown Rabies Vaccine 1
Unspecified De-Wormer 1
Praziquantel + Pyrantel Pamoate 1
Cyclosporine 1
Trimeprazine Tartrate;Prednisolone 1
Amoxicillin Trihydrate;Clavulanate Potassium ( K-Clavulanate) 1
Unspecified Gabapentin 1
Unspecified Adequan 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Persistent cough (#2224 of 2,481 by report volume); death-coded 22.2%. PlainBreed reaction plate · report volume stamp 18 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →