Reaction profile

The FDA adverse-event record for glucose intolerance

Name: Glucose intolerance - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

11 FDA reports name glucose intolerance, a lower-volume reaction in the CVM extract (VeDDRA 392). Plate stamps and neighbourhood peers follow.

#2421 of 2,481
by report volume (all reactions): 11
reports citing this reaction: 18.2%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Glucose intolerance has 11 reports now versus 11 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: +0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Glucose intolerance changes

FDA AER · VeDDRA plate

Code 392 VOL-TRACE

VOL-TRACE · DEATH-ELEV · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 11 reports
DEATH-ELEV 18.2%
BOTTOM-DECILE #2421/2481
PHOTO-FINISH ABNORMAL PANCREATIC S…
SPECIES-DOG Dog · 6
DRUG-LEAD Trilostane · 3
DESK-WIDE 8 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: ABNORMAL PANCREATIC SPECIFIC LIPASE (PLI) (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Glucose intolerance

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Glucose intolerance

What the FDA AER plate says about Glucose intolerance

Signature read: 11 reports place Glucose intolerance in the lower third of FDA AER volume (#2421 of 2,481). Report volume is lower-third scale: 11 named reports in the openFDA extract. 2 of 11 reports were death-coded (18.2% of named reports, not a population mortality rate). Nearest volume peer: ABNORMAL PANCREATIC SPECIFIC LIPASE (PLI) (±0 reports). Lead species Dog (6). Lead co-reported drug Trilostane (3).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Trilostane appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 6

Cat 5

Breeds Most Affected

Domestic Shorthair 4

Dog (other) 1

Terrier - Yorkshire 1

Spaniel - King Charles Cavalier 1

Terrier (unspecified) 1

Pug 1

Domestic Longhair 1

Maltese 1

Associated Drugs

Trilostane 3

Insulin 3

Cefovecin 2

Oclacitinib Maleate 2

Phytosphingosine Hydrochloride 1

Buprenorphine 1

Meloxicam 1

Ketamine 1

Diazepam 1

Sevoflurane 1

Eye Medication 1

Maropitant Citrate 1

Famotidine 1

Polysulfated Glycosaminoglycan 1

Subcutaneous Fluids 1

Injectable Antibiotic 1

Cyclosporine 1

Milbemycin Oxime + Praziquantel 1

Frunevetmab 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Glucose intolerance (#2421 of 2,481 by report volume); death-coded 18.2%. PlainBreed reaction plate · report volume stamp 11 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →