Reaction profile

The FDA adverse-event record for abnormal menace reflex test

941 FDA adverse-event reports reference abnormal menace reflex test (VeDDRA 1096). See the species, breeds, and drugs most associated with it below.

941
reports citing this reaction
23.8%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
941
Total Reports
224
Deaths
23.8%
Death Rate

Species Most Affected

Dog 703
Cat 228
Horse 7
Cattle 2
Pig 1

Breeds Most Affected

Domestic Shorthair 146
Crossbred Canine/dog 48
Retriever - Labrador 45
Chihuahua 36
Shih Tzu 26
Retriever - Golden 24
Terrier - Yorkshire 22
Shepherd Dog - German 22
Maltese 22
Shepherd Dog - Australian 21

Associated Drugs

Milbemycin Oxime + Spinosad 106
Maropitant Citrate 80
Carprofen 60
Ivermectin 58
Spinosad 51
Fluralaner Chew Tablets 48
Buprenorphine 44
Enrofloxacin 39
Selamectin 38
Sarolaner 38
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 38
Bedinvetmab 38
Afoxolaner 35
Gabapentin 35
Fluralaner 13.64% 12-Week Chew 34
Cefovecin 32
Oclacitinib Maleate 32
Pyrantel Pamoate;Sarolaner 30
Prednisone 29
Moxidectin 29

Abnormal menace reflex test Reaction Insights

941 reports name Abnormal menace reflex test; 224 recorded a death outcome (23.8% of reported events, not a population-level mortality rate). VeDDRA code: 1096.

By species: Dog (703 reports), Cat (228 reports), Horse (7 reports). By breed: Domestic Shorthair (146), Crossbred Canine/dog (48), Retriever - Labrador (45).

Most co-reported drugs: Milbemycin Oxime + Spinosad (106 reports), Maropitant Citrate (80 reports), Carprofen (60 reports), Ivermectin (58 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.