Abnormal menace reflex test

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VeDDRA Code: 1096

941 adverse event reports referencing this reaction

941
Total Reports
224
Deaths
2380.0%
Death Rate

Species Most Affected

Dog 703
Cat 228
Horse 7
Cattle 2
Pig 1

Breeds Most Affected

Domestic Shorthair 146
Crossbred Canine/dog 48
Retriever - Labrador 45
Chihuahua 36
Shih Tzu 26
Retriever - Golden 24
Terrier - Yorkshire 22
Shepherd Dog - German 22
Maltese 22
Shepherd Dog - Australian 21

Associated Drugs

Milbemycin Oxime + Spinosad 106
Maropitant Citrate 80
Carprofen 60
Ivermectin 58
Spinosad 51
Fluralaner Chew Tablets 48
Buprenorphine 44
Enrofloxacin 39
Selamectin 38
Sarolaner 38
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 38
Bedinvetmab 38
Afoxolaner 35
Gabapentin 35
Fluralaner 13.64% 12-Week Chew 34
Cefovecin 32
Oclacitinib Maleate 32
Pyrantel Pamoate;Sarolaner 30
Prednisone 29
Moxidectin 29

Data Summary

Metric Value
Total reports referencing reaction 941
Reports with fatal outcome 224
Case-fatality rate (reported events) 2380.0%
Species observed 5
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1096.

Abnormal menace reflex test Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 941 adverse event reports that reference Abnormal menace reflex test as a reaction term, including 224 reports with a death outcome — a 2380.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1096, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Abnormal menace reflex test appears most frequently in reports for Dog (703 reports), Cat (228 reports), Horse (7 reports) — with Dog dominating at 703 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (146), Crossbred Canine/dog (48), Retriever - Labrador (45). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Abnormal menace reflex test are Milbemycin Oxime + Spinosad (106 reports), Maropitant Citrate (80 reports), Carprofen (60 reports), Ivermectin (58 reports), with Milbemycin Oxime + Spinosad appearing alongside this reaction in 106 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial