Reaction profile

The FDA adverse-event record for jaundice

937 FDA adverse-event reports reference jaundice (VeDDRA 501). See the species, breeds, and drugs most associated with it below.

937
reports citing this reaction
42.8%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
937
Total Reports
401
Deaths
42.8%
Death Rate

Species Most Affected

Dog 706
Cat 216
Human 5
Cattle 4
Horse 4
Other Reptiles 1
Mule 1

Breeds Most Affected

Retriever - Labrador 193
Domestic Shorthair 141
Crossbred Canine/dog 49
Pit Bull 23
Shepherd Dog - German 22
Retriever - Golden 18
Domestic Longhair 18
Shepherd Dog - Australian 17
Chihuahua 16
Beagle 15

Associated Drugs

Carprofen 313
Maropitant Citrate 135
Famotidine 47
Moxidectin 46
Milbemycin Oxime + Spinosad 45
Tramadol 39
Sam-E, Silybin, Vitamin E, Zinc 39
Metronidazole 36
Cefovecin 35
Afoxolaner 34
Gabapentin 33
Prednisone 32
Oclacitinib Maleate 31
Fluralaner Chew Tablets 29
Enrofloxacin 27
Spinosad 27
Sucralfate 27
Itraconazole 26
Isoflurane 25
Doxycycline 23

Jaundice Reaction Insights

937 reports name Jaundice; 401 recorded a death outcome (42.8% of reported events, not a population-level mortality rate). VeDDRA code: 501.

By species: Dog (706 reports), Cat (216 reports), Human (5 reports). By breed: Retriever - Labrador (193), Domestic Shorthair (141), Crossbred Canine/dog (49).

Most co-reported drugs: Carprofen (313 reports), Maropitant Citrate (135 reports), Famotidine (47 reports), Moxidectin (46 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.