Reaction profile

The FDA adverse-event record for liver nodules

73 FDA adverse-event reports reference liver nodules (VeDDRA 2904). See the species, breeds, and drugs most associated with it below.

73
reports citing this reaction
39.7%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
73
Total Reports
29
Deaths
39.7%
Death Rate

Species Most Affected

Dog 59
Cat 14

Breeds Most Affected

Retriever - Labrador 10
Crossbred Canine/dog 8
Domestic Shorthair 5
Retriever - Golden 5
Collie - Border 5
Terrier (unspecified) 3
Siberian Husky 3
Boxer (German Boxer) 2
Siamese 2
Shih Tzu 2

Associated Drugs

Bedinvetmab 23
Carprofen 18
Maropitant Citrate 15
Gabapentin 13
Capromorelin 9
Trilostane 8
Ondansetron 7
Ursodiol 7
Enrofloxacin 7
Buprenorphine 6
Ampicillin/Sulbactam 6
Pyrantel Pamoate;Sarolaner 5
Metronidazole 5
Fluralaner 13.64% 12-Week Chew 5
Frunevetmab 5
Liver Supplement 5
Leptospirosis Vaccine 5
Grapiprant 4
Intravenous Fluids 4
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 4

Liver nodules Reaction Insights

73 reports name Liver nodules; 29 recorded a death outcome (39.7% of reported events, not a population-level mortality rate). VeDDRA code: 2904.

By species: Dog (59 reports), Cat (14 reports). By breed: Retriever - Labrador (10), Crossbred Canine/dog (8), Domestic Shorthair (5).

Most co-reported drugs: Bedinvetmab (23 reports), Carprofen (18 reports), Maropitant Citrate (15 reports), Gabapentin (13 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.