Reaction profile

The FDA adverse-event record for slow reflexes

84 FDA adverse-event reports reference slow reflexes (VeDDRA 674). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1481 of 2,481
by report volume (all reactions)
84
reports citing this reaction
16.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Slow reflexes has 84 reports now versus 80 in that prior snapshot: 4 more (5.0%).

Report change
+4
Death-coded reports
+1
Death-coded share
+0.4 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Slow reflexes changes

FDA AER · VeDDRA plate

Code 674 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 84 reports
  • DEATH-ELEV 16.7%
  • MID-PACK #1481/2481
  • PHOTO-FINISH Lichenification
  • SPECIES-DOG Dog · 63
  • DRUG-LEAD Bedinvetmab · 12
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Lichenification (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Slow reflexes

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Dental plaque · near85Lichenification · near84Pulmonary hypertension · near84Slow reflexes · this reaction84Destructive behaviour · near83Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Slow reflexes

What the FDA AER plate says about Slow reflexes

Signature read: report volume at 84 (#1481 of 2,481) is the standout scale stamp on Slow reflexes. Report volume sits in the middle third of the reaction corpus. 14 of 84 reports were death-coded (16.7% of named reports, not a population mortality rate). Nearest volume peer: Lichenification (±0 reports). Lead species Dog (63). Lead co-reported drug Bedinvetmab (12).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Bedinvetmab appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 63
Cat 16
Horse 3
Pig 1
Human 1

Breeds Most Affected

Domestic Shorthair 13
Retriever - Labrador 7
Terrier - Yorkshire 4
Chihuahua 4
Pit Bull 3
Crossbred Canine/dog 3
Shepherd Dog - Australian 3
Horse (unknown) 2
Retriever - Golden 2
Shepherd Dog - German 2

Associated Drugs

Bedinvetmab 12
Milbemycin Oxime + Spinosad 11
Maropitant Citrate 9
Pyrantel Pamoate;Sarolaner 7
Spinosad 6
Gabapentin 6
Carprofen 4
Robenacoxib 4
Buprenorphine 4
Moxidectin 3
Glucosamine + Chondroitin 3
Selamectin 3
Cefovecin 3
Oclacitinib Maleate 3
Afoxolaner 3
Rabies Vaccine 3
Miconazole Nitrate + Polymyxin B Sulfate + Prednisolone Acetate 2
Rabies Virus, Kv 2
Prednisone 2
Midazolam 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Slow reflexes, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (84 here).

Similar death-coded share

Nearest other reactions by death-coded share (16.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Slow reflexes (#1481 of 2,481 by report volume); death-coded 16.7%. PlainBreed reaction plate · report volume stamp 84 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →