Reaction profile

The FDA adverse-event record for swollen joint

156 FDA adverse-event reports reference swollen joint (VeDDRA 1816). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1166 of 2,481
by report volume (all reactions)
156
reports citing this reaction
16.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Swollen joint has 156 reports now versus 148 in that prior snapshot: 8 more (5.4%).

Report change
+8
Death-coded reports
+0
Death-coded share
−0.9 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Swollen joint changes

FDA AER · VeDDRA plate

Code 1816 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 156 reports
  • DEATH-ELEV 16.7%
  • MID-PACK #1166/2481
  • PHOTO-FINISH Abnormal necropsy fin…
  • SPECIES-DOG Dog · 101
  • DRUG-LEAD Bedinvetmab · 46
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal necropsy finding (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Swollen joint

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Abnormal necropsy fin… · near156Delayed healing · near156Lip disorder NOS · near156Retinal degeneration · near156Swollen joint · this reaction156Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Swollen joint

What the FDA AER plate says about Swollen joint

Signature read: 26 death-coded reports is the most distinctive absolute-outcome stamp on Swollen joint. Report volume sits in the middle third of the reaction corpus. 26 of 156 reports were death-coded (16.7% of named reports, not a population mortality rate). Nearest volume peer: Abnormal necropsy finding (±0 reports). Lead species Dog (101). Lead co-reported drug Bedinvetmab (46).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Bedinvetmab appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 101
Cat 22
Cattle 19
Horse 10
Human 3
Chicken 1

Breeds Most Affected

Retriever - Labrador 20
Domestic Shorthair 14
Shepherd Dog - German 10
Cattle (other) 7
Retriever - Golden 7
Shar Pei 5
Holstein-Friesian also known as Holstein 5
Chihuahua 5
Unknown 4
Mixed (Cattle) 4

Associated Drugs

Bedinvetmab 46
Carprofen 30
Frunevetmab 20
Gabapentin 19
Oclacitinib Maleate 18
Lotilaner 14
Prednisone 9
Doxycycline 8
Tulathromycin 7
Deracoxib 6
Maropitant Citrate 6
Polysulfated Glycosaminoglycan 6
Ilunocitinib 6
Tramadol 5
Enrofloxacin 5
Rabies Vaccine 5
Ceftiofur Crystalline Free Acid 4
Grapiprant 4
Anti-Il31 Mab Mcs Lot #1283563 4
Milbemycin Oxime + Praziquantel 4

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Swollen joint, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (156 here).

Similar death-coded share

Nearest other reactions by death-coded share (16.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Swollen joint (#1166 of 2,481 by report volume); death-coded 16.7%. PlainBreed reaction plate · death-coded report count stamp 26 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →