Reaction profile
The FDA adverse-event record for difficulty to rise
665 FDA reports name difficulty to rise, a high-volume reaction in the CVM extract (VeDDRA 2726). Plate stamps and neighbourhood peers follow.
- #535 of 2,481
- by report volume (all reactions)
- 665
- reports citing this reaction
- 22.0%
- death-coded share
- Dog
- most-affected species
Release-over-release change
What changed in the latest FDA data snapshot
PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Difficulty to rise has 665 reports now versus 637 in that prior snapshot: 28 more (4.4%).
- Report change
- +28
- Death-coded reports
- +5
- Death-coded share
- −0.2 pts
This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.
Subscribe to Difficulty to rise changesFDA AER · VeDDRA plate
Code 2726 VOL-MID
VOL-MID · DEATH-HOT · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL
- VOL-MID 665 reports
- DEATH-HOT 22.0%
- UPPER-Q #535/2481
- PHOTO-FINISH Disoriented state
- SPECIES-DOG Dog · 636
- DRUG-LEAD Bedinvetmab · 322
- DESK-WIDE 20 breeds
- BOOK-FULL 8/8 fields
Nearest volume peer: Disoriented state (±1 reports)
Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.
High-volume neighbourhood around Difficulty to rise
Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.
What the FDA AER plate says about Difficulty to rise
Signature read: 146 death-coded reports is a heavy tail count for Difficulty to rise in the CVM extract. Report volume is upper-third scale: 665 named reports in the openFDA extract. 146 of 665 reports were death-coded (22.0% of named reports, not a population mortality rate). Nearest volume peer: Disoriented state (±1 reports). Lead species Dog (636). Lead co-reported drug Bedinvetmab (322).
Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Bedinvetmab appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.
Species Most Affected
Breeds Most Affected
Associated Drugs
Nationwide reactions with similar profiles
Two openFDA-derived peer sets for Difficulty to rise, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).
Similar report volume
Nearest other reactions by FDA report count (665 here).
Similar death-coded share
Nearest other reactions by death-coded share (22.0% here), distinct from the volume row.
What to do with this reaction
- Compare Difficulty to rise's report profile against similar reactions nationwide. See similar reactions
- Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
- Browse the full reaction directory to compare report counts across reaction types. All reactions
A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.
Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025
Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →