Alopecia local

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VeDDRA Code: 900

1,303 adverse event reports referencing this reaction

1,303
Total Reports
45
Deaths
350.0%
Death Rate

Species Most Affected

Dog 806
Cat 442
Cattle 27
Horse 26
Donkey 2

Breeds Most Affected

Domestic Shorthair 309
Retriever - Labrador 97
Crossbred Canine/dog 52
Shepherd Dog - German 45
Domestic Longhair 36
Chihuahua 31
Boxer (German Boxer) 28
Retriever - Golden 27
Beagle 25
Domestic Mediumhair 22

Associated Drugs

Frunevetmab 167
Imidacloprid + Moxidectin 106
Oclacitinib Maleate 103
Milbemycin Oxime + Spinosad 89
Afoxolaner 88
Fluralaner Chew Tablets 65
Cefovecin 64
Selamectin 63
Prednisone 51
Carprofen 41
Moxidectin 38
Trilostane 37
Bedinvetmab 35
Gabapentin 30
Emodepside + Praziquantel 28
Fluralaner Spot-On Solution 27
Selamectin;Sarolaner 25
Ivermectin + Pyrantel As Pamoate Salt 22
Methylprednisolone Acetate 21
Spinosad 20

Data Summary

Metric Value
Total reports referencing reaction 1,303
Reports with fatal outcome 45
Case-fatality rate (reported events) 350.0%
Species observed 5
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 900.

Alopecia local Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 1,303 adverse event reports that reference Alopecia local as a reaction term, including 45 reports with a death outcome — a 350.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 900, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Alopecia local appears most frequently in reports for Dog (806 reports), Cat (442 reports), Cattle (27 reports) — with Dog dominating at 806 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (309), Retriever - Labrador (97), Crossbred Canine/dog (52). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Alopecia local are Frunevetmab (167 reports), Imidacloprid + Moxidectin (106 reports), Oclacitinib Maleate (103 reports), Milbemycin Oxime + Spinosad (89 reports), with Frunevetmab appearing alongside this reaction in 167 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial