Reaction profile

The FDA adverse-event record for attractiveness to males

31 FDA adverse-event reports reference attractiveness to males (VeDDRA 2061). See the species, breeds, and drugs most associated with it below.

31
reports citing this reaction
9.7%
death-coded share
Dog
most-affected species
Estriol Tablets
most-associated drug
Verify with FDA CVM →
31
Total Reports
3
Deaths
9.7%
Death Rate

Species Most Affected

Dog 29
Cattle 2

Breeds Most Affected

Crossbred Canine/dog 8
Doberman Pinscher 2
Poodle - Miniature 2
Pug 2
Terrier - Yorkshire 1
Sheepdog - Shetland 1
Cattle (other) 1
Retriever - Labrador 1
Terrier - Fox (unspecified) 1
Holstein-Friesian also known as Holstein 1

Associated Drugs

Estriol Tablets 26
Trilostane 2
Estriol 1
Progesterone; Estradiol Benzoate 1
Melengestrol Acetate 1
Estradiol Benzoate; Trenbolone Acetate 1
Bedinvetmab 1

Attractiveness to males Reaction Insights

31 reports name Attractiveness to males; 3 recorded a death outcome (9.7% of reported events, not a population-level mortality rate). VeDDRA code: 2061.

By species: Dog (29 reports), Cattle (2 reports). By breed: Crossbred Canine/dog (8), Doberman Pinscher (2), Poodle - Miniature (2).

Most co-reported drugs: Estriol Tablets (26 reports), Trilostane (2 reports), Estriol (1 reports), Progesterone; Estradiol Benzoate (1 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.