Reaction profile

The FDA adverse-event record for perinatal mortality nos

31 FDA adverse-event reports reference perinatal mortality nos (VeDDRA 783). See the species, breeds, and drugs most associated with it below.

31
reports citing this reaction
83.9%
death-coded share
Dog
most-affected species
Spinosad
most-associated drug
Verify with FDA CVM →
31
Total Reports
26
Deaths
83.9%
Death Rate

Species Most Affected

Dog 21
Cattle 4
Horse 2
Pig 2
Cat 1
Sheep 1

Breeds Most Affected

Dog (unknown) 5
Pug 5
Retriever - Labrador 2
Crossbred Bovine/Cattle 2
Domestic (unspecified) 1
Sheep (unknown) 1
Terrier - Boston 1
Terrier - Yorkshire 1
Crossbred Canine/dog 1
Coonhound (unspecified) 1

Associated Drugs

Spinosad 10
Ivermectin, Pyrantel Pamoate, Praziquantel 4
Ivermectin 2
Spinosad, Milbemycin 2
Imidacloprid, Moxidectin 1
Deracoxib 1
Tiletamine, Zolazepam 1
Milbemycin, Lufenuron 1
Firocoxib 1
Florfenicol 1
Diclofenac 1
Novobiocin, Penicillin G Procaine 1
Fenbendazole 1
Monensin Sodium 1
Tilmicosin 1
Lufenuron + Milbemycin Oxime 1
Alfaxalone 1

Perinatal mortality NOS Reaction Insights

31 reports name Perinatal mortality NOS; 26 recorded a death outcome (83.9% of reported events, not a population-level mortality rate). VeDDRA code: 783.

By species: Dog (21 reports), Cattle (4 reports), Horse (2 reports). By breed: Dog (unknown) (5), Pug (5), Retriever - Labrador (2).

Most co-reported drugs: Spinosad (10 reports), Ivermectin, Pyrantel Pamoate, Praziquantel (4 reports), Ivermectin (2 reports), Spinosad, Milbemycin (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.