Papilloma

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VeDDRA Code: 920

500 adverse event reports referencing this reaction

500
Total Reports
11
Deaths
220.0%
Death Rate

Species Most Affected

Dog 499
Cat 1

Breeds Most Affected

Retriever - Labrador 61
Retriever - Golden 56
Terrier - Bull - American Pit 38
Bulldog - French 36
Shepherd Dog - German 23
Crossbred Canine/dog 18
Dog (unknown) 17
Bulldog 16
Boxer (German Boxer) 15
Pug 12

Associated Drugs

Oclacitinib Maleate 411
Anti-Il31 Mab Mcs Lot #1283563 43
Cyclosporine A 36
Cyclosporine 19
Milbemycin Oxime + Spinosad 14
Cephalexin 14
Prednisone 13
Afoxolaner 13
Carprofen 13
Immunotherapy 12
Gabapentin 10
Hydroxyzine 9
Trilostane 8
Ketoconazole 8
Fluralaner 8
Cefpodoxime 7
Diphenhydramine Hcl 7
Cefpodoxime Proxetil 7
Azithromycin 7
Antibiotic 7

Data Summary

Metric Value
Total reports referencing reaction 500
Reports with fatal outcome 11
Case-fatality rate (reported events) 220.0%
Species observed 2
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 920.

Papilloma Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 500 adverse event reports that reference Papilloma as a reaction term, including 11 reports with a death outcome — a 220.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 920, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Papilloma appears most frequently in reports for Dog (499 reports), Cat (1 reports) — with Dog dominating at 499 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (61), Retriever - Golden (56), Terrier - Bull - American Pit (38). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Papilloma are Oclacitinib Maleate (411 reports), Anti-Il31 Mab Mcs Lot #1283563 (43 reports), Cyclosporine A (36 reports), Cyclosporine (19 reports), with Oclacitinib Maleate appearing alongside this reaction in 411 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial