ALBUMIN/GLOBULIN RATIO LO, BLD

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VeDDRA Code: 99164

46 adverse event reports referencing this reaction

46
Total Reports
6
Deaths
1300.0%
Death Rate

Species Most Affected

Dog 43
Horse 2
Cattle 1

Breeds Most Affected

Retriever - Labrador 6
Shepherd Dog - German 4
Pug 3
Spitz - German Pomeranian 2
Chihuahua 2
Pit Bull 1
Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne)) 1
Deutsche Dogge, Great Dane 1
Retriever - Golden 1
Havanese 1

Associated Drugs

Milbemycin Oxime + Spinosad 10
Afoxolaner 6
Spinosad 4
Fluralaner Chew Tablets 4
Meloxicam 3
Ivermectin + Pyrantel As Pamoate Salt 3
Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg 2
Firocoxib 2
Robenacoxib 2
Hydroxyzine Hcl 1
Cephalexin 1
Vaccines (Unknown) 1
Firocoxib 227 Mg Chewable 1
Ivermectin/Pyrantel Pamoate Chewable 68Mcg/163Mg 1
Ivermectin/Pyrantel Pamoate Chewable 136Mcg/326Mg 1
Pergolide Mesylate 1
Clenbuterol Hydrochloride 1
Ivermectin/Pyrantel Pamoate/Praziquantel 1
Cyclosporine A 1
Fipronil 1

Data Summary

Metric Value
Total reports referencing reaction 46
Reports with fatal outcome 6
Case-fatality rate (reported events) 1300.0%
Species observed 3
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 99164.

ALBUMIN/GLOBULIN RATIO LO, BLD Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 46 adverse event reports that reference ALBUMIN/GLOBULIN RATIO LO, BLD as a reaction term, including 6 reports with a death outcome — a 1300.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 99164, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

ALBUMIN/GLOBULIN RATIO LO, BLD appears most frequently in reports for Dog (43 reports), Horse (2 reports), Cattle (1 reports) — with Dog dominating at 43 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (6), Shepherd Dog - German (4), Pug (3). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with ALBUMIN/GLOBULIN RATIO LO, BLD are Milbemycin Oxime + Spinosad (10 reports), Afoxolaner (6 reports), Spinosad (4 reports), Fluralaner Chew Tablets (4 reports), with Milbemycin Oxime + Spinosad appearing alongside this reaction in 10 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial