Torn ligament

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VeDDRA Code: 2581

212 adverse event reports referencing this reaction

212
Total Reports
17
Deaths
800.0%
Death Rate

Species Most Affected

Dog 208
Cat 2
Horse 1
Human 1

Breeds Most Affected

Retriever - Labrador 37
Dog (unknown) 13
Crossbred Canine/dog 13
Retriever - Golden 10
Boxer (German Boxer) 8
Beagle 6
Terrier - Yorkshire 5
Maltese 5
Terrier - Bull - American Pit 5
Collie - Border 5

Associated Drugs

Bedinvetmab 63
Carprofen 36
Trilostane 30
Gabapentin 25
Milbemycin Oxime + Spinosad 19
Grapiprant 19
Milbemycin Oxime + Praziquantel 19
Oclacitinib Maleate 16
Afoxolaner 13
Fluralaner Chew Tablets 9
Deracoxib 8
Anti-Il31 Mab Mcs Lot #1283563 7
Fluralaner 13.64% 12-Week Chew 7
Prednisone 5
Tramadol 5
Ivermectin + Pyrantel As Pamoate Salt 5
Imidacloprid + Moxidectin 4
Pimobendan 4
Fish Oil 4
Metronidazole 4

Data Summary

Metric Value
Total reports referencing reaction 212
Reports with fatal outcome 17
Case-fatality rate (reported events) 800.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2581.

Torn ligament Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 212 adverse event reports that reference Torn ligament as a reaction term, including 17 reports with a death outcome — a 800.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2581, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Torn ligament appears most frequently in reports for Dog (208 reports), Cat (2 reports), Horse (1 reports) — with Dog dominating at 208 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (37), Dog (unknown) (13), Crossbred Canine/dog (13). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Torn ligament are Bedinvetmab (63 reports), Carprofen (36 reports), Trilostane (30 reports), Gabapentin (25 reports), with Bedinvetmab appearing alongside this reaction in 63 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial