Reaction profile

The FDA adverse-event record for acute (interstitial) pneumonia/pleuropneumonia

40 FDA reports name acute (interstitial) pneumonia/pleuropneumonia, a lower-volume reaction in the CVM extract (VeDDRA 2295). Plate stamps and neighbourhood peers follow.

#1842 of 2,481
by report volume (all reactions)
40
reports citing this reaction
77.5%
death-coded share
Cattle
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Acute (interstitial) pneumonia/pleuropneumonia has 40 reports now versus 39 in that prior snapshot: 1 more (2.6%).

Report change
+1
Death-coded reports
+1
Death-coded share
+0.6 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Acute (interstitial) pneumonia/pleuropneumonia changes

FDA AER · VeDDRA plate

Code 2295 VOL-TRACE

VOL-TRACE · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-CATTLE · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 40 reports
  • DEATH-HOT 77.5%
  • MID-PACK #1842/2481
  • PHOTO-FINISH Anxious state of mind
  • SPECIES-CATTLE Cattle · 22
  • DRUG-LEAD Tulathromycin · 16
  • DESK-WIDE 19 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Anxious state of mind (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Acute pneumonia/pleuropneumonia

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Acute (interstitial)… · this…40Anxious state of mind · near40Direct Coombs test, p… · near40Endocrine neoplasm · near40Hepatic encephalopathy · near40Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Acute (interstitial) pneumonia/pleuropneumonia

Acute (interstitial) pneumonia/pleuropneumonia: high death-coded share in the FDA AER plate

Signature read: Acute (interstitial) pneumonia/pleuropneumonia's 77.5% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 40 named reports in the openFDA extract. Death-coded share is upper-third: 31 of 40 reports (77.5% of named reports). Nearest volume peer: Anxious state of mind (±0 reports). Lead species Cattle (22). Lead co-reported drug Tulathromycin (16).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cattle 22
Dog 11
Horse 4
Pig 2
Cat 1

Breeds Most Affected

Cattle (other) 7
Crossbred Bovine/Cattle 5
Thoroughbred 4
Aberdeen Angus 3
Mixed (Cattle) 3
Dachshund - Miniature 2
Cattle (unknown) 2
Collie - Border 2
Crossbred Canine/dog 2
Boxer (German Boxer) 1

Associated Drugs

Tulathromycin 16
Ceftiofur 9
Monensin Sodium 8
Lubabegron Fumarate 8
Florfenicol 7
Trenbolone; Estradiol; Tylosin Tartrate 5
Tylosin Phosphate 5
Bedinvetmab 5
Gabapentin 5
Dexamethasone 5
Doramectin 4
Ceftiofur Crystalline Free Acid 4
Moxidectin 3
Bovine Rhinotracheitis-Virus Diarrhea Vaccine 3
Clostridium Chauvoei + Septicum + Haemolyticum + Novyi + Tetani + Perfringens Types C & D Bacterin-Toxoid 3
Fenbendazole 3
Flunixin Meglumine,Florfenicol 3
Tildipirosin Injectable 3
Prednisone 3
Flunixin Meglumine 3

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Acute (interstitial) pneumonia/pleuropneumonia (#1842 of 2,481 by report volume); death-coded 77.5%. PlainBreed reaction plate · death-coded share stamp 77.5% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →