Reaction profile

The FDA adverse-event record for acute (interstitial) pneumonia/pleuropneumonia

32 FDA adverse-event reports reference acute (interstitial) pneumonia/pleuropneumonia (VeDDRA 2295). See the species, breeds, and drugs most associated with it below.

32
reports citing this reaction
71.9%
death-coded share
Cattle
most-affected species
Monensin Sodium
most-associated drug
Verify with FDA CVM →
32
Total Reports
23
Deaths
71.9%
Death Rate

Species Most Affected

Cattle 15
Dog 10
Horse 4
Pig 2
Cat 1

Breeds Most Affected

Crossbred Bovine/Cattle 5
Thoroughbred 4
Aberdeen Angus 3
Dachshund - Miniature 2
Cattle (unknown) 2
Collie - Border 2
Mixed (Cattle) 2
Crossbred Canine/dog 2
Boxer (German Boxer) 1
Domestic Shorthair 1

Associated Drugs

Monensin Sodium 6
Tulathromycin 6
Trenbolone; Estradiol; Tylosin Tartrate 5
Ceftiofur 5
Bedinvetmab 5
Gabapentin 5
Doramectin 4
Ceftiofur Crystalline Free Acid 4
Moxidectin 3
Tylosin Phosphate 3
Bovine Rhinotracheitis-Virus Diarrhea Vaccine 3
Clostridium Chauvoei + Septicum + Haemolyticum + Novyi + Tetani + Perfringens Types C & D Bacterin-Toxoid 3
Fenbendazole 3
Flunixin Meglumine,Florfenicol 3
Prednisone 3
Florfenicol 3
Flunixin Meglumine 3
Trilostane 2
Fenbendazol Suspension 2
Clostr Perf*2/Clos Others*4 Kb 2

Acute (interstitial) pneumonia/pleuropneumonia Reaction Insights

32 reports name Acute (interstitial) pneumonia/pleuropneumonia; 23 recorded a death outcome (71.9% of reported events, not a population-level mortality rate). VeDDRA code: 2295.

By species: Cattle (15 reports), Dog (10 reports), Horse (4 reports). By breed: Crossbred Bovine/Cattle (5), Thoroughbred (4), Aberdeen Angus (3).

Most co-reported drugs: Monensin Sodium (6 reports), Tulathromycin (6 reports), Trenbolone; Estradiol; Tylosin Tartrate (5 reports), Ceftiofur (5 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.