Reaction profile

The FDA adverse-event record for loss of bowel control

449 FDA reports name loss of bowel control, a high-volume reaction in the CVM extract (VeDDRA 1070). Plate stamps and neighbourhood peers follow.

#682 of 2,481
by report volume (all reactions)
449
reports citing this reaction
24.9%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Loss of bowel control has 449 reports now versus 437 in that prior snapshot: 12 more (2.7%).

Report change
+12
Death-coded reports
+4
Death-coded share
+0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Loss of bowel control changes

FDA AER · VeDDRA plate

Code 1070 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 449 reports
  • DEATH-HOT 24.9%
  • MID-PACK #682/2481
  • PHOTO-FINISH PR-KIDNEY(S), LESION(…
  • SPECIES-DOG Dog · 402
  • DRUG-LEAD Bedinvetmab · 55
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: PR-KIDNEY(S), LESION(S) (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Loss of bowel control

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Loss of bowel control · this…449PR-KIDNEY(S), LESION(… · near449Temporary blindness · near449Application site grea… · near448Arched back · near448Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Loss of bowel control

Loss of bowel control: high death-coded share in the FDA AER plate

Signature read: 112 death-coded reports is a heavy tail count for Loss of bowel control in the CVM extract. Report volume is upper-third scale: 449 named reports in the openFDA extract. Death-coded share is upper-third: 112 of 449 reports (24.9% of named reports). Nearest volume peer: PR-KIDNEY(S), LESION(S) (±0 reports). Lead species Dog (402). Lead co-reported drug Bedinvetmab (55).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 402
Cat 43
Horse 3
Duck 1

Breeds Most Affected

Retriever - Labrador 48
Crossbred Canine/dog 35
Chihuahua 25
Domestic Shorthair 23
Shepherd Dog - German 20
Dog (unknown) 15
Retriever - Golden 14
Boxer (German Boxer) 13
Terrier - Yorkshire 11
Terrier - Bull - American Pit 11

Associated Drugs

Bedinvetmab 55
Milbemycin Oxime + Spinosad 54
Afoxolaner 52
Ivermectin + Pyrantel As Pamoate Salt 35
Moxidectin 33
Maropitant Citrate 26
Carprofen 24
Pyrantel Pamoate;Sarolaner 22
Gabapentin 19
Fluralaner 13.64% 12-Week Chew 17
Milbemycin Oxime + Praziquantel 16
Fluralaner Chew Tablets 15
Sarolaner 13
Spinosad 12
Melarsomine Dihydrochloride 10
Lotilaner 10
Famotidine 9
Grapiprant 9
Trilostane 8
Rabies Virus, Kv 8

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Loss of bowel control, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (449 here).

Similar death-coded share

Nearest other reactions by death-coded share (24.9% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Loss of bowel control (#682 of 2,481 by report volume); death-coded 24.9%. PlainBreed reaction plate · death-coded report count stamp 112 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →