Reaction profile

The FDA adverse-event record for abnormal posture

220 FDA adverse-event reports reference abnormal posture (VeDDRA 2395). See the species, breeds, and drugs most associated with it below.

220
reports citing this reaction
14.5%
death-coded share
Dog
most-affected species
Afoxolaner
most-associated drug
Verify with FDA CVM →
220
Total Reports
32
Deaths
14.5%
Death Rate

Species Most Affected

Dog 174
Cat 36
Horse 5
Goat 2
Turkey 1
Cattle 1
Rabbit 1

Breeds Most Affected

Domestic Shorthair 22
Retriever - Labrador 19
Retriever - Golden 11
Crossbred Canine/dog 11
Terrier - Yorkshire 8
Shepherd Dog - German 8
Schnauzer - Miniature 7
Chihuahua 7
Shih Tzu 7
Shepherd Dog - Australian 7

Associated Drugs

Afoxolaner 28
Milbemycin Oxime + Spinosad 24
Ivermectin + Pyrantel As Pamoate Salt 20
Bedinvetmab 16
Carprofen 15
Buprenorphine 14
Maropitant Citrate 12
Fluralaner Chew Tablets 10
Gabapentin 10
Melarsomine Dihydrochloride 9
Moxidectin 7
Milbemycin Oxime + Praziquantel 7
Fluralaner 13.64% 12-Week Chew 7
Sarolaner 6
Prednisone 6
Eprinomectin + Esafoxolaner + Praziquantel 6
Oclacitinib Maleate 5
Meloxicam 5
Ivermectin + Pyrantel 5
Nitenpyram 5

Abnormal posture Reaction Insights

220 reports name Abnormal posture; 32 recorded a death outcome (14.5% of reported events, not a population-level mortality rate). VeDDRA code: 2395.

By species: Dog (174 reports), Cat (36 reports), Horse (5 reports). By breed: Domestic Shorthair (22), Retriever - Labrador (19), Retriever - Golden (11).

Most co-reported drugs: Afoxolaner (28 reports), Milbemycin Oxime + Spinosad (24 reports), Ivermectin + Pyrantel As Pamoate Salt (20 reports), Bedinvetmab (16 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.