Reaction profile

The FDA adverse-event record for cerebral vascular accident

17 FDA adverse-event reports reference cerebral vascular accident (VeDDRA 638). See the species, breeds, and drugs most associated with it below.

17
reports citing this reaction
47.1%
death-coded share
Dog
most-affected species
Afoxolaner
most-associated drug
Verify with FDA CVM →
17
Total Reports
8
Deaths
47.1%
Death Rate

Species Most Affected

Dog 15
Horse 1
Cat 1

Breeds Most Affected

Crossbred Canine/dog 5
Retriever - Golden 2
Greyhound 1
Pekingese 1
Spaniel - Cocker English 1
Holsteiner 1
Domestic Shorthair 1
Boxer (German Boxer) 1
Poodle - Miniature 1
Maltese 1

Associated Drugs

Afoxolaner 3
Milbemycin Oxime + Spinosad 2
Fluralaner Chew Tablets 2
Carprofen 2
Bedinvetmab 2
Prednisone 2
Pregabalin 2
Fish Oil 1
Phenylpropanolamine Hcl 1
Firocoxib 1
Afoxolaner 68 Mg Chewable Tablets 1
Amoxicillin, Clavulanate 1
Fusidic Acid, Framycetin, Nystatin 1
Ivermectin + Pyrantel As Pamoate Salt 1
Vit E/ Selenite Inj Solution 1
Emodepside + Praziquantel 1
Unspecified Vaccines 1
Fluids 1
Anti-Emetic 1
Famotidine 1

Cerebral vascular accident Reaction Insights

17 reports name Cerebral vascular accident; 8 recorded a death outcome (47.1% of reported events, not a population-level mortality rate). VeDDRA code: 638.

By species: Dog (15 reports), Horse (1 reports), Cat (1 reports). By breed: Crossbred Canine/dog (5), Retriever - Golden (2), Greyhound (1).

Most co-reported drugs: Afoxolaner (3 reports), Milbemycin Oxime + Spinosad (2 reports), Fluralaner Chew Tablets (2 reports), Carprofen (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.