Shallow breathing

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VeDDRA Code: 2481

403 adverse event reports referencing this reaction

403
Total Reports
104
Deaths
2580.0%
Death Rate

Species Most Affected

Dog 321
Cat 75
Horse 3
Rabbit 2
Cattle 1
Other Rodents 1

Breeds Most Affected

Domestic Shorthair 43
Retriever - Labrador 30
Crossbred Canine/dog 19
Dog (unknown) 17
Chihuahua 15
Shih Tzu 15
Shepherd Dog - German 14
Boxer (German Boxer) 12
Terrier (unspecified) 12
Shepherd Dog - Australian 12

Associated Drugs

Milbemycin Oxime + Spinosad 30
Maropitant Citrate 26
Moxidectin 25
Afoxolaner 24
Gabapentin 21
Bedinvetmab 21
Fluralaner Chew Tablets 19
Pyrantel Pamoate;Sarolaner 19
Fluralaner 13.64% 12-Week Chew 17
Isoflurane 16
Buprenorphine 16
Carprofen 16
Milbemycin Oxime + Praziquantel 16
Sarolaner 15
Cefovecin 14
Selamectin 12
Ivermectin + Pyrantel As Pamoate Salt 11
Oclacitinib Maleate 10
Butorphanol 10
Dexmedetomidine 9

Data Summary

Metric Value
Total reports referencing reaction 403
Reports with fatal outcome 104
Case-fatality rate (reported events) 2580.0%
Species observed 6
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2481.

Shallow breathing Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 403 adverse event reports that reference Shallow breathing as a reaction term, including 104 reports with a death outcome — a 2580.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2481, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Shallow breathing appears most frequently in reports for Dog (321 reports), Cat (75 reports), Horse (3 reports) — with Dog dominating at 321 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (43), Retriever - Labrador (30), Crossbred Canine/dog (19). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Shallow breathing are Milbemycin Oxime + Spinosad (30 reports), Maropitant Citrate (26 reports), Moxidectin (25 reports), Afoxolaner (24 reports), with Milbemycin Oxime + Spinosad appearing alongside this reaction in 30 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial