Reaction profile

The FDA adverse-event record for shallow breathing

403 FDA adverse-event reports reference shallow breathing (VeDDRA 2481). See the species, breeds, and drugs most associated with it below.

403
reports citing this reaction
25.8%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
403
Total Reports
104
Deaths
25.8%
Death Rate

Species Most Affected

Dog 321
Cat 75
Horse 3
Rabbit 2
Cattle 1
Other Rodents 1

Breeds Most Affected

Domestic Shorthair 43
Retriever - Labrador 30
Crossbred Canine/dog 19
Dog (unknown) 17
Chihuahua 15
Shih Tzu 15
Shepherd Dog - German 14
Boxer (German Boxer) 12
Terrier (unspecified) 12
Shepherd Dog - Australian 12

Associated Drugs

Milbemycin Oxime + Spinosad 30
Maropitant Citrate 26
Moxidectin 25
Afoxolaner 24
Gabapentin 21
Bedinvetmab 21
Fluralaner Chew Tablets 19
Pyrantel Pamoate;Sarolaner 19
Fluralaner 13.64% 12-Week Chew 17
Isoflurane 16
Buprenorphine 16
Carprofen 16
Milbemycin Oxime + Praziquantel 16
Sarolaner 15
Cefovecin 14
Selamectin 12
Ivermectin + Pyrantel As Pamoate Salt 11
Oclacitinib Maleate 10
Butorphanol 10
Dexmedetomidine 9

Shallow breathing Reaction Insights

403 reports name Shallow breathing; 104 recorded a death outcome (25.8% of reported events, not a population-level mortality rate). VeDDRA code: 2481.

By species: Dog (321 reports), Cat (75 reports), Horse (3 reports). By breed: Domestic Shorthair (43), Retriever - Labrador (30), Crossbred Canine/dog (19).

Most co-reported drugs: Milbemycin Oxime + Spinosad (30 reports), Maropitant Citrate (26 reports), Moxidectin (25 reports), Afoxolaner (24 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.