Reaction profile

The FDA adverse-event record for lack of efficacy (endoparasite) - toxocara/toxascaris

77 FDA adverse-event reports reference lack of efficacy (endoparasite) - toxocara/toxascaris (VeDDRA 2826). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1520 of 2,481
by report volume (all reactions)
77
reports citing this reaction
0.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Lack of efficacy (endoparasite) - Toxocara/Toxascaris has 77 reports now versus 66 in that prior snapshot: 11 more (16.7%).

Report change
+11
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Lack of efficacy (endoparasite) - Toxocara/Toxascaris changes

FDA AER · VeDDRA plate

Code 2826 VOL-LOW

VOL-LOW · DEATH-RARE · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 77 reports
  • DEATH-RARE 0.0%
  • MID-PACK #1520/2481
  • PHOTO-FINISH Application site twit…
  • SPECIES-DOG Dog · 73
  • DRUG-LEAD Pyrantel Pamoate;… · 30
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Application site twitching (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Lack of efficacy - Toxocara/Toxascaris

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Application site twit… · near77Cutaneous oedema · near77Dermal plaque · near77Drug preparation error · near77Lack of efficacy (end… · thi…77Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Lack of efficacy (endoparasite) - Toxocara/Toxascaris

Lack of efficacy (endoparasite) - Toxocara/Toxascaris: low death-coded share in the FDA AER plate

Signature read: Lack of efficacy (endoparasite) - Toxocara/Toxascaris's 0.0% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 0 of 77 reports (0.0% of named reports). Nearest volume peer: Application site twitching (±0 reports). Lead species Dog (73). Lead co-reported drug Pyrantel Pamoate;Sarolaner (30).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Pyrantel Pamoate;Sarolaner appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 73
Cat 4

Breeds Most Affected

Retriever - Labrador 13
Retriever - Golden 8
Siberian Husky 5
Dog (unknown) 4
Crossbred Canine/dog 3
Hound - Basset 3
Spaniel - King Charles Cavalier 3
Terrier (unspecified) 3
Terrier - Yorkshire 2
Domestic Shorthair 2

Associated Drugs

Pyrantel Pamoate;Sarolaner 30
Milbemycin Oxime + Praziquantel 26
Lotilaner 7
Moxidectin 4
Pyrantel 4
Lotilaner,Moxidectin,Praziquantel,Pyrantel Pamoate 4
Milbemycin Oxime 3
Febantel + Praziquantel + Pyrantel Pamoate 3
Eprinomectin + Esafoxolaner + Praziquantel 3
Fenbendazole 3
Ponazuril 3
Sarolaner,Moxidectin,Pyrantel 2
Fluralaner 2
Imidacloprid + Moxidectin 2
Oclacitinib Maleate 2
Ivermectin + Praziquantel + Pyrantel Pamoate 2
Milbemycin Oxime,Praziquantel Micronized 2
Selamectin;Sarolaner 1
Ivermectin + Pyrantel 1
Milbemycin/Lufenuron/Pzq Chew 1

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Lack of efficacy (endoparasite) - Toxocara/Toxascaris, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (77 here).

Similar death-coded share

Nearest other reactions by death-coded share (0.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Lack of efficacy (endoparasite) - Toxocara/Toxascaris (#1520 of 2,481 by report volume); death-coded 0.0%. PlainBreed reaction plate · death-coded share stamp 0.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →