Lack of efficacy (endoparasite) - Toxocara/Toxascaris

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VeDDRA Code: 2826

59 adverse event reports referencing this reaction

59
Total Reports
0
Deaths
0.0%
Death Rate

Species Most Affected

Dog 55
Cat 4

Breeds Most Affected

Retriever - Labrador 11
Retriever - Golden 6
Crossbred Canine/dog 3
Hound - Basset 3
Spaniel - King Charles Cavalier 3
Siberian Husky 2
Domestic Shorthair 2
Terrier - Yorkshire 2
Dachshund (unspecified) 2
Shepherd Dog - German 2

Associated Drugs

Pyrantel Pamoate;Sarolaner 26
Milbemycin Oxime + Praziquantel 22
Lotilaner 6
Moxidectin 4
Milbemycin Oxime 3
Eprinomectin + Esafoxolaner + Praziquantel 3
Febantel + Praziquantel + Pyrantel Pamoate 2
Fluralaner 2
Oclacitinib Maleate 2
Milbemycin Oxime,Praziquantel Micronized 2
Selamectin;Sarolaner 1
Ivermectin + Pyrantel 1
Milbemycin/Lufenuron/Pzq Chew 1
Ivermectin / Pyrantel Tablets 1
Fluralaner 13.64% 12-Week Chew 1
Sarolaner,Moxidectin,Pyrantel 1
Pyrantel 1
Imidacloprid + Moxidectin 1
Pyrantel Pamoate/Praziquantel 1
Fenbendazole 1

Data Summary

Metric Value
Total reports referencing reaction 59
Reports with fatal outcome 0
Case-fatality rate (reported events) 0.0%
Species observed 2
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2826.

Lack of efficacy (endoparasite) - Toxocara/Toxascaris Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 59 adverse event reports that reference Lack of efficacy (endoparasite) - Toxocara/Toxascaris as a reaction term, including 0 reports with a death outcome — a 0.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2826, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Lack of efficacy (endoparasite) - Toxocara/Toxascaris appears most frequently in reports for Dog (55 reports), Cat (4 reports) — with Dog dominating at 55 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (11), Retriever - Golden (6), Crossbred Canine/dog (3). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Lack of efficacy (endoparasite) - Toxocara/Toxascaris are Pyrantel Pamoate;Sarolaner (26 reports), Milbemycin Oxime + Praziquantel (22 reports), Lotilaner (6 reports), Moxidectin (4 reports), with Pyrantel Pamoate;Sarolaner appearing alongside this reaction in 26 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial