Reaction profile

The FDA adverse-event record for lack of efficacy (endoparasite) - toxocara/toxascaris

59 FDA adverse-event reports reference lack of efficacy (endoparasite) - toxocara/toxascaris (VeDDRA 2826). See the species, breeds, and drugs most associated with it below.

59
reports citing this reaction
0.0%
death-coded share
Dog
most-affected species
Pyrantel Pamoate;Sarolaner
most-associated drug
Verify with FDA CVM →
59
Total Reports
0
Deaths
0.0%
Death Rate

Species Most Affected

Dog 55
Cat 4

Breeds Most Affected

Retriever - Labrador 11
Retriever - Golden 6
Crossbred Canine/dog 3
Hound - Basset 3
Spaniel - King Charles Cavalier 3
Siberian Husky 2
Domestic Shorthair 2
Terrier - Yorkshire 2
Dachshund (unspecified) 2
Shepherd Dog - German 2

Associated Drugs

Pyrantel Pamoate;Sarolaner 26
Milbemycin Oxime + Praziquantel 22
Lotilaner 6
Moxidectin 4
Milbemycin Oxime 3
Eprinomectin + Esafoxolaner + Praziquantel 3
Febantel + Praziquantel + Pyrantel Pamoate 2
Fluralaner 2
Oclacitinib Maleate 2
Milbemycin Oxime,Praziquantel Micronized 2
Selamectin;Sarolaner 1
Ivermectin + Pyrantel 1
Milbemycin/Lufenuron/Pzq Chew 1
Ivermectin / Pyrantel Tablets 1
Fluralaner 13.64% 12-Week Chew 1
Sarolaner,Moxidectin,Pyrantel 1
Pyrantel 1
Imidacloprid + Moxidectin 1
Pyrantel Pamoate/Praziquantel 1
Fenbendazole 1

Lack of efficacy (endoparasite) - Toxocara/Toxascaris Reaction Insights

59 reports name Lack of efficacy (endoparasite) - Toxocara/Toxascaris; 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). VeDDRA code: 2826.

By species: Dog (55 reports), Cat (4 reports). By breed: Retriever - Labrador (11), Retriever - Golden (6), Crossbred Canine/dog (3).

Most co-reported drugs: Pyrantel Pamoate;Sarolaner (26 reports), Milbemycin Oxime + Praziquantel (22 reports), Lotilaner (6 reports), Moxidectin (4 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.