Reaction profile

The FDA adverse-event record for welt

454 FDA adverse-event reports reference welt (VeDDRA 1875). See the species, breeds, and drugs most associated with it below.

454
reports citing this reaction
2.6%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
454
Total Reports
12
Deaths
2.6%
Death Rate

Species Most Affected

Dog 400
Human 23
Cat 22
Horse 8
Goat 1

Breeds Most Affected

Chihuahua 29
Pit Bull 28
Retriever - Labrador 28
Crossbred Canine/dog 27
Unknown 24
Terrier - Bull - American Pit 21
Terrier - Yorkshire 19
Dachshund (unspecified) 18
Boxer (German Boxer) 16
Retriever - Golden 12

Associated Drugs

Milbemycin Oxime + Spinosad 68
Moxidectin 58
Afoxolaner 41
Oclacitinib Maleate 34
Spinosad 26
Anti-Il31 Mab Mcs Lot #1283563 22
Ivermectin + Pyrantel As Pamoate Salt 19
Fluralaner Chew Tablets 18
Prednisone 17
Maropitant Citrate 15
Milbemycin Oxime + Praziquantel 15
Fluralaner 13.64% 12-Week Chew 15
Selamectin 14
Nitenpyram 14
Sarolaner 12
Pyrantel Pamoate;Sarolaner 11
Carprofen 9
Imidacloprid + Moxidectin 9
Diphenhydramine Hcl 9
Ivermectin 8

Welt Reaction Insights

454 reports name Welt; 12 recorded a death outcome (2.6% of reported events, not a population-level mortality rate). VeDDRA code: 1875.

By species: Dog (400 reports), Human (23 reports), Cat (22 reports). By breed: Chihuahua (29), Pit Bull (28), Retriever - Labrador (28).

Most co-reported drugs: Milbemycin Oxime + Spinosad (68 reports), Moxidectin (58 reports), Afoxolaner (41 reports), Oclacitinib Maleate (34 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.