Reaction profile

The FDA adverse-event record for motor dysfunction nos

126 FDA adverse-event reports reference motor dysfunction nos (VeDDRA 1620). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1285 of 2,481
by report volume (all reactions)
126
reports citing this reaction
21.4%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Motor dysfunction NOS has 126 reports now versus 122 in that prior snapshot: 4 more (3.3%).

Report change
+4
Death-coded reports
+1
Death-coded share
+0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Motor dysfunction NOS changes

FDA AER · VeDDRA plate

Code 1620 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 126 reports
  • DEATH-HOT 21.4%
  • MID-PACK #1285/2481
  • PHOTO-FINISH Extensor rigidity
  • SPECIES-DOG Dog · 103
  • DRUG-LEAD Milbemycin Oxime… · 27
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Extensor rigidity (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Motor dysfunction NOS

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Extensor rigidity · near126Flatulence, bloating… · near126Hiccup · near126Infertility NOS · near126Motor dysfunction NOS · this…126Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Motor dysfunction NOS

What the FDA AER plate says about Motor dysfunction NOS

Signature read: death-coded share at 21.4% is the most distinctive outcome stamp on Motor dysfunction NOS. Report volume sits in the middle third of the reaction corpus. 27 of 126 reports were death-coded (21.4% of named reports, not a population mortality rate). Nearest volume peer: Extensor rigidity (±0 reports). Lead species Dog (103). Lead co-reported drug Milbemycin Oxime + Spinosad (27).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 103
Cat 19
Human 1
Horse 1
Goat 1
Cattle 1

Breeds Most Affected

Retriever - Labrador 14
Domestic Shorthair 12
Chihuahua 9
Crossbred Canine/dog 9
Boxer (German Boxer) 4
Terrier - Yorkshire 4
Shepherd Dog - German 4
Dachshund (unspecified) 3
Unknown 3
Sheepdog - Shetland 3

Associated Drugs

Milbemycin Oxime + Spinosad 27
Bedinvetmab 13
Afoxolaner 10
Pyrantel Pamoate;Sarolaner 9
Carprofen 8
Gabapentin 7
Ivermectin + Pyrantel As Pamoate Salt 6
Fluralaner Chew Tablets 6
Sarolaner 6
Meloxicam 5
Selamectin;Sarolaner 5
Spinosad 4
Maropitant Citrate 4
Lotilaner 4
Ivermectin 3
Selamectin 3
Doxycycline 3
Grapiprant 3
Anti-Il31 Mab Mcs Lot #1283563 3
Buprenorphine 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Motor dysfunction NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (126 here).

Similar death-coded share

Nearest other reactions by death-coded share (21.4% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Motor dysfunction NOS (#1285 of 2,481 by report volume); death-coded 21.4%. PlainBreed reaction plate · death-coded share stamp 21.4% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →