Platelet disorder NOS

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VeDDRA Code: 2423

310 adverse event reports referencing this reaction

310
Total Reports
63
Deaths
2030.0%
Death Rate

Species Most Affected

Dog 277
Cat 31
Human 1
Goat 1

Breeds Most Affected

Retriever - Labrador 28
Crossbred Canine/dog 22
Domestic Shorthair 19
Retriever - Golden 16
Shih Tzu 16
Chihuahua 14
Pit Bull 11
Dachshund (unspecified) 8
Bichon Frise 8
Shepherd Dog - Australian 8

Associated Drugs

Oclacitinib Maleate 40
Maropitant Citrate 39
Carprofen 39
Fluralaner Chew Tablets 26
Prednisone 24
Gabapentin 23
Bedinvetmab 21
Enrofloxacin 18
Afoxolaner 16
Milbemycin Oxime + Praziquantel 16
Metronidazole 15
Famotidine 14
Trilostane 14
Fluralaner 13.64% 12-Week Chew 14
Lotilaner 14
Moxidectin 12
Maropitant 12
Doxycycline 11
Ivermectin + Pyrantel As Pamoate Salt 11
Rabies Vaccine 11

Data Summary

Metric Value
Total reports referencing reaction 310
Reports with fatal outcome 63
Case-fatality rate (reported events) 2030.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2423.

Platelet disorder NOS Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 310 adverse event reports that reference Platelet disorder NOS as a reaction term, including 63 reports with a death outcome — a 2030.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2423, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Platelet disorder NOS appears most frequently in reports for Dog (277 reports), Cat (31 reports), Human (1 reports) — with Dog dominating at 277 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (28), Crossbred Canine/dog (22), Domestic Shorthair (19). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Platelet disorder NOS are Oclacitinib Maleate (40 reports), Maropitant Citrate (39 reports), Carprofen (39 reports), Fluralaner Chew Tablets (26 reports), with Oclacitinib Maleate appearing alongside this reaction in 40 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial