Difficulty in micturition

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VeDDRA Code: 1410

82 adverse event reports referencing this reaction

82
Total Reports
18
Deaths
2200.0%
Death Rate

Species Most Affected

Dog 60
Cat 19
Leopard 1
Horse 1
Human 1

Breeds Most Affected

Domestic Shorthair 9
Retriever - Labrador 6
Chihuahua 5
Retriever - Golden 4
Maltese 3
Terrier - West Highland White 3
Crossbred Canine/dog 3
Poodle (unspecified) 3
Terrier - Bull - American Pit 2
Unknown 2

Associated Drugs

Bedinvetmab 11
Robenacoxib 9
Milbemycin Oxime + Spinosad 8
Buprenorphine 8
Gabapentin 7
Prednisone 6
Grapiprant 6
Cyclosporine 6
Oclacitinib Maleate 5
Carprofen 5
Maropitant Citrate 4
Omeprazole 4
Ivermectin + Pyrantel As Pamoate Salt 4
Fluralaner 13.64% 12-Week Chew 4
Afoxolaner 3
Imidacloprid + Moxidectin 3
Meloxicam 3
Lotilaner 3
Isoflurane 3
Bexagliflozin 3

Data Summary

Metric Value
Total reports referencing reaction 82
Reports with fatal outcome 18
Case-fatality rate (reported events) 2200.0%
Species observed 5
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1410.

Difficulty in micturition Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 82 adverse event reports that reference Difficulty in micturition as a reaction term, including 18 reports with a death outcome — a 2200.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1410, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Difficulty in micturition appears most frequently in reports for Dog (60 reports), Cat (19 reports), Leopard (1 reports) — with Dog dominating at 60 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (9), Retriever - Labrador (6), Chihuahua (5). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Difficulty in micturition are Bedinvetmab (11 reports), Robenacoxib (9 reports), Milbemycin Oxime + Spinosad (8 reports), Buprenorphine (8 reports), with Bedinvetmab appearing alongside this reaction in 11 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial