Reaction profile

The FDA adverse-event record for heavy breathing

863 FDA reports name heavy breathing, a high-volume reaction in the CVM extract (VeDDRA 2776). Plate stamps and neighbourhood peers follow.

#438 of 2,481
by report volume (all reactions)
863
reports citing this reaction
22.2%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Heavy breathing has 863 reports now versus 815 in that prior snapshot: 48 more (5.9%).

Report change
+48
Death-coded reports
+11
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Heavy breathing changes

FDA AER · VeDDRA plate

Code 2776 VOL-MID

VOL-MID · DEATH-HOT · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 863 reports
  • DEATH-HOT 22.2%
  • UPPER-Q #438/2481
  • PHOTO-FINISH Swelling around eye
  • SPECIES-DOG Dog · 642
  • DRUG-LEAD Bedinvetmab · 121
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Swelling around eye (±1 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Heavy breathing

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Gastroenteritis · near865Swelling around eye · near864Heavy breathing · this react…863Peritonitis · near859Muscle weakness NOS · near858Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Heavy breathing

What the FDA AER plate says about Heavy breathing

Signature read: 192 death-coded reports is a heavy tail count for Heavy breathing in the CVM extract. Report volume is upper-third scale: 863 named reports in the openFDA extract. 192 of 863 reports were death-coded (22.2% of named reports, not a population mortality rate). Nearest volume peer: Swelling around eye (±1 reports). Lead species Dog (642). Lead co-reported drug Bedinvetmab (121).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Bedinvetmab appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 642
Cat 179
Cattle 23
Horse 17
Pig 1
Human 1

Breeds Most Affected

Domestic Shorthair 106
Retriever - Labrador 69
Shepherd Dog - German 38
Crossbred Canine/dog 36
Retriever - Golden 31
Chihuahua 27
Terrier - Yorkshire 22
Dog (unknown) 21
Bulldog - French 20
Boxer (German Boxer) 19

Associated Drugs

Bedinvetmab 121
Nitenpyram 73
Moxidectin 65
Pyrantel Pamoate;Sarolaner 57
Gabapentin 57
Maropitant Citrate 46
Fluralaner 13.64% 12-Week Chew 39
Afoxolaner 38
Carprofen 37
Oclacitinib Maleate 37
Prednisone 28
Ivermectin + Pyrantel As Pamoate Salt 25
Lotilaner 23
Trilostane 22
Melarsomine Dihydrochloride 21
Milbemycin Oxime + Praziquantel 21
Buprenorphine 21
Grapiprant 18
Enrofloxacin 18
Butorphanol 17

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Heavy breathing, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (863 here).

Similar death-coded share

Nearest other reactions by death-coded share (22.2% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Heavy breathing (#438 of 2,481 by report volume); death-coded 22.2%. PlainBreed reaction plate · death-coded report count stamp 192 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →