Reaction profile

The FDA adverse-event record for heavy breathing

765 FDA adverse-event reports reference heavy breathing (VeDDRA 2776). See the species, breeds, and drugs most associated with it below.

765
reports citing this reaction
22.2%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
765
Total Reports
170
Deaths
22.2%
Death Rate

Species Most Affected

Dog 566
Cat 163
Cattle 20
Horse 14
Pig 1
Human 1

Breeds Most Affected

Domestic Shorthair 97
Retriever - Labrador 57
Shepherd Dog - German 33
Crossbred Canine/dog 30
Retriever - Golden 26
Chihuahua 24
Terrier - Yorkshire 20
Dog (unknown) 19
Boxer (German Boxer) 17
Bulldog - French 16

Associated Drugs

Bedinvetmab 100
Nitenpyram 66
Moxidectin 60
Pyrantel Pamoate;Sarolaner 53
Gabapentin 47
Maropitant Citrate 39
Fluralaner 13.64% 12-Week Chew 37
Carprofen 32
Afoxolaner 31
Oclacitinib Maleate 31
Ivermectin + Pyrantel As Pamoate Salt 23
Melarsomine Dihydrochloride 20
Prednisone 20
Lotilaner 20
Trilostane 18
Enrofloxacin 17
Buprenorphine 17
Milbemycin Oxime + Praziquantel 16
Butorphanol 15
Grapiprant 14

Heavy breathing Reaction Insights

765 reports name Heavy breathing; 170 recorded a death outcome (22.2% of reported events, not a population-level mortality rate). VeDDRA code: 2776.

By species: Dog (566 reports), Cat (163 reports), Cattle (20 reports). By breed: Domestic Shorthair (97), Retriever - Labrador (57), Shepherd Dog - German (33).

Most co-reported drugs: Bedinvetmab (100 reports), Nitenpyram (66 reports), Moxidectin (60 reports), Pyrantel Pamoate;Sarolaner (53 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.