Reaction profile

The FDA adverse-event record for pr-pleural effusion

35 FDA adverse-event reports reference pr-pleural effusion (VeDDRA 99668). See the species, breeds, and drugs most associated with it below.

35
reports citing this reaction
82.9%
death-coded share
Cat
most-affected species
Cefovecin Sodium
most-associated drug
Verify with FDA CVM →
35
Total Reports
29
Deaths
82.9%
Death Rate

Species Most Affected

Cat 19
Dog 14
Horse 2

Breeds Most Affected

Domestic (unspecified) 11
Domestic Shorthair 4
Crossbred Canine/dog 2
Domestic Longhair 2
Shepherd Dog - Australian 2
Mastiff 1
Siamese 1
Dachshund (unspecified) 1
Shih Tzu 1
Cat (unknown) 1

Associated Drugs

Cefovecin Sodium 7
Cefovecin 7
Dexamethasone 3
Enrofloxacin 3
Oclacitinib Maleate 3
Dexmedetomidine Hydrochloride 2
Meloxicam 2
Carprofen 2
Imidacloprid + Moxidectin 2
Butorphanol 2
Furosemide 2
Methylprednisolone Acetate 2
Selamectin 2
Deracoxib 1
Spinosad 1
Lufenuron 1
Atipamezole 1
Tiletamine, Zolazepam 1
Vitamin A 1
Vitamin D 1

PR-PLEURAL EFFUSION Reaction Insights

35 reports name PR-PLEURAL EFFUSION; 29 recorded a death outcome (82.9% of reported events, not a population-level mortality rate). VeDDRA code: 99668.

By species: Cat (19 reports), Dog (14 reports), Horse (2 reports). By breed: Domestic (unspecified) (11), Domestic Shorthair (4), Crossbred Canine/dog (2).

Most co-reported drugs: Cefovecin Sodium (7 reports), Cefovecin (7 reports), Dexamethasone (3 reports), Enrofloxacin (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.