Reaction profile

The FDA adverse-event record for pr-pleural effusion

36 FDA reports name pr-pleural effusion, a lower-volume reaction in the CVM extract (VeDDRA 99668). Plate stamps and neighbourhood peers follow.

#1913 of 2,481
by report volume (all reactions)
36
reports citing this reaction
83.3%
death-coded share
Cat
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. PR-PLEURAL EFFUSION has 36 reports now versus 36 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to PR-PLEURAL EFFUSION changes

FDA AER · VeDDRA plate

Code 99668 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-CAT · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 36 reports
  • DEATH-HOT 83.3%
  • LOWER-Q #1913/2481
  • PHOTO-FINISH Abnormal birth weight
  • SPECIES-CAT Cat · 20
  • DRUG-LEAD Cefovecin Sodium · 7
  • DESK-WIDE 19 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal birth weight (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around PR-PLEURAL EFFUSION

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abnormal birth weight · near36Adaptor, leaking · near36Blood dyscrasia NOS · near36Contact dermatitis · near36PR-PLEURAL EFFUSION · this r…36Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around PR-PLEURAL EFFUSION

PR-PLEURAL EFFUSION: high death-coded share in the FDA AER plate

Signature read: PR-PLEURAL EFFUSION's 83.3% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 36 named reports in the openFDA extract. Death-coded share is upper-third: 30 of 36 reports (83.3% of named reports). Nearest volume peer: Abnormal birth weight (±0 reports). Lead species Cat (20). Lead co-reported drug Cefovecin Sodium (7).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cat 20
Dog 14
Horse 2

Breeds Most Affected

Domestic (unspecified) 11
Domestic Shorthair 5
Crossbred Canine/dog 2
Domestic Longhair 2
Shepherd Dog - Australian 2
Mastiff 1
Siamese 1
Dachshund (unspecified) 1
Shih Tzu 1
Cat (unknown) 1

Associated Drugs

Cefovecin Sodium 7
Cefovecin 7
Dexamethasone 3
Enrofloxacin 3
Oclacitinib Maleate 3
Dexmedetomidine Hydrochloride 2
Meloxicam 2
Carprofen 2
Imidacloprid + Moxidectin 2
Butorphanol 2
Furosemide 2
Methylprednisolone Acetate 2
Selamectin 2
Deracoxib 1
Spinosad 1
Tiletamine, Zolazepam 1
Lufenuron 1
Atipamezole 1
Vitamin A 1
Vitamin D 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for PR-PLEURAL EFFUSION (#1913 of 2,481 by report volume); death-coded 83.3%. PlainBreed reaction plate · death-coded share stamp 83.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →