Reaction profile

The FDA adverse-event record for drug administration error

4,419 FDA reports name drug administration error, a high-volume reaction in the CVM extract (VeDDRA 99819). Plate stamps and neighbourhood peers follow.

#110 of 2,481
by report volume (all reactions)
4,419
reports citing this reaction
4.5%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Drug administration error has 4,419 reports now versus 4,419 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Drug administration error changes

FDA AER · VeDDRA plate

Code 99819 VOL-MID

VOL-MID · DEATH-LOW · TOP-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 4,419 reports
  • DEATH-LOW 4.5%
  • TOP-DECILE #110/2481
  • PHOTO-FINISH Intentional misuse
  • SPECIES-DOG Dog · 3,443
  • DRUG-LEAD Fluralaner Chew T… · 733
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Intentional misuse (±24 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Drug administration error

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Erythema (for urticar… · near4509Nausea · near4502Intentional misuse · near4443Drug administration e… · thi…4419Skin lesion NOS · near4336Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Drug administration error

Drug administration error: low death-coded share in the FDA AER plate

Signature read: 4,419 reports place Drug administration error in the upper third of FDA AER volume (#110 of 2,481). Report volume is upper-third scale: 4,419 named reports in the openFDA extract. Death-coded share is lower-third: 197 of 4,419 reports (4.5% of named reports). Nearest volume peer: Intentional misuse (±24 reports). Lead species Dog (3,443). Lead co-reported drug Fluralaner Chew Tablets (733).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Fluralaner Chew Tablets appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 3,443
Cat 702
Human 98
Cattle 54
Horse 33
Unknown 25
Goat 15
Pig 8
Sheep 8
Rabbit 8

Breeds Most Affected

Crossbred Canine/dog 424
Domestic Shorthair 368
Chihuahua 264
Retriever - Labrador 228
Terrier - Yorkshire 191
Dog (unknown) 159
Shih Tzu 146
Unknown 138
Shepherd Dog - German 123
Retriever - Golden 117

Associated Drugs

Fluralaner Chew Tablets 733
Fluralaner 13.64% 12-Week Chew 720
Oclacitinib Maleate 275
Milbemycin Oxime + Spinosad 250
Imidacloprid + Moxidectin 231
Spinosad 209
Selamectin 167
Nitenpyram 150
Fluralaner Spot-On Solution 125
Insulin Injectable Vial 92
Praziquantel + Pyrantel Pamoate 82
Carprofen 81
Dexmedetomidine Hydrochloride 78
Afoxolaner 78
Febantel + Praziquantel + Pyrantel Pamoate 68
Ivermectin + Pyrantel As Pamoate Salt 67
Emodepside + Praziquantel 56
Butorphanol Tartrate 51
Ivermectin 47
Fluralaner 13.64% Chew Tablets 45

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Drug administration error, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (4,419 here).

Similar death-coded share

Nearest other reactions by death-coded share (4.5% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Drug administration error (#110 of 2,481 by report volume); death-coded 4.5%. PlainBreed reaction plate · report volume stamp 4,419 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →