Reaction profile

The FDA adverse-event record for hyperventilation

259 FDA adverse-event reports reference hyperventilation (VeDDRA 1177). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#918 of 2,481
by report volume (all reactions)
259
reports citing this reaction
13.5%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Hyperventilation has 259 reports now versus 255 in that prior snapshot: 4 more (1.6%).

Report change
+4
Death-coded reports
+0
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Hyperventilation changes

FDA AER · VeDDRA plate

Code 1177 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 259 reports
  • DEATH-ELEV 13.5%
  • MID-PACK #918/2481
  • PHOTO-FINISH Lack of efficacy (ect…
  • SPECIES-DOG Dog · 178
  • DRUG-LEAD Nitenpyram · 18
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Lack of efficacy (ectoparasite) - Demodex (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Hyperventilation

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Hyperventilation · this reac…259Lack of efficacy (ect… · near259Hyperthyroidism · near258Apathy · near257Injection site infect… · near257Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Hyperventilation

What the FDA AER plate says about Hyperventilation

Signature read: 35 death-coded reports is the most distinctive absolute-outcome stamp on Hyperventilation. Report volume sits in the middle third of the reaction corpus. 35 of 259 reports were death-coded (13.5% of named reports, not a population mortality rate). Nearest volume peer: Lack of efficacy (ectoparasite) - Demodex (±0 reports). Lead species Dog (178). Lead co-reported drug Nitenpyram (18).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Nitenpyram appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 178
Cat 54
Horse 25
Cattle 1
Human 1

Breeds Most Affected

Domestic Shorthair 28
Crossbred Canine/dog 15
Retriever - Labrador 15
Dog (unknown) 12
Quarter Horse 10
Domestic Longhair 9
Boxer (German Boxer) 7
Domestic Mediumhair 7
Dachshund (unspecified) 7
Terrier - Yorkshire 6

Associated Drugs

Nitenpyram 18
Milbemycin Oxime + Spinosad 16
Afoxolaner 13
Detomidine Hydrochloride 13
Butorphanol 12
Moxidectin 12
Cefovecin 11
Carprofen 11
Spinosad 10
Fluralaner 13.64% 12-Week Chew 10
Propofol 9
Dexmedetomidine Hydrochloride 8
Bedinvetmab 8
Selamectin 7
Maropitant Citrate 7
Ivermectin + Pyrantel As Pamoate Salt 7
Butorphanol Tartrate 7
Gabapentin 7
Isoflurane 6
Lotilaner 6

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Hyperventilation, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (259 here).

Similar death-coded share

Nearest other reactions by death-coded share (13.5% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Hyperventilation (#918 of 2,481 by report volume); death-coded 13.5%. PlainBreed reaction plate · death-coded report count stamp 35 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →