Reaction profile

The FDA adverse-event record for product syringe issue

Name: Product syringe issue - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

1,017 FDA reports name product syringe issue, a high-volume reaction in the CVM extract (VeDDRA 99860). Plate stamps and neighbourhood peers follow.

#388 of 2,481
by report volume (all reactions): 1,017
reports citing this reaction: 0.3%
death-coded share: Unknown
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Product syringe issue has 1,017 reports now versus 999 in that prior snapshot: 18 more (1.8%).

Report change: +18
Death-coded reports: +0
Death-coded share: −0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Product syringe issue changes

FDA AER · VeDDRA plate

Code 99860 VOL-MID

VOL-MID · DEATH-RARE · UPPER-Q · PHOTO-FINISH · SPECIES-UNKNOWN · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-MID 1,017 reports
DEATH-RARE 0.3%
UPPER-Q #388/2481
PHOTO-FINISH Paddling
SPECIES-UNKNOWN Unknown · 957
DRUG-LEAD Meloxicam · 246
DESK-WIDE 20 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Paddling (±8 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Product syringe issue

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Product syringe issue

Product syringe issue: low death-coded share in the FDA AER plate

Signature read: Product syringe issue's 0.3% death-coded share is among the lowest in the openFDA reaction corpus. Report volume is upper-third scale: 1,017 named reports in the openFDA extract. Death-coded share is lower-third: 3 of 1,017 reports (0.3% of named reports). Nearest volume peer: Paddling (±8 reports). Lead species Unknown (957). Lead co-reported drug Meloxicam (246).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Meloxicam appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Unknown 957

Cat 26

Human 13

Dog 11

Horse 6

Cattle 4

Breeds Most Affected

Unknown 970

Domestic Shorthair 8

Cat (unknown) 7

Dog (unknown) 5

Domestic (unspecified) 4

Domestic Longhair 4

Quarter Horse 3

Horse (unknown) 2

Cattle (unknown) 2

Crossbred Bovine/Cattle 1

Associated Drugs

Meloxicam 246

Cyclosporine 173

Sometribove 71

Hyaluronate Sodium 71

Eprinomectin + Esafoxolaner + Praziquantel 48

Capromorelin Tartrate 39

Lufenuron 28

Device: Syringe 23

Vetpen Starter Kit 22

Sodium Hyaluronate 22

Velagliflozin Proline Monohydrate 21

Omeprazole 20

Metronidazole 17

Cyclosporine A 16

Itraconazole 14

Cephapirin Sodium 13

Ivermectin 12

Praziquantel; Moxidectin 11

Molidustat 11

Dirlotapide 10

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Product syringe issue, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (1,017 here).

Paddling 1,009 Pulmonary oedema 1,009 Decreased haemoglobin 1,007 Itchy skin 1,005

Similar death-coded share

Nearest other reactions by death-coded share (0.3% here), distinct from the volume row.

INEFFECTIVE, HOOKS 0.3% INEFFECTIVE, WHIPS 0.3% Lack of efficacy (ectoparasite) - flea 0.3% Lack of efficacy (endoparasite) - roundworm NOS 0.3%

What to do with this reaction

Compare Product syringe issue's report profile against similar reactions nationwide. See similar reactions
Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Product syringe issue (#388 of 2,481 by report volume); death-coded 0.3%. PlainBreed reaction plate · death-coded share stamp 0.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →