Contamination, Foreign Object

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VeDDRA Code: 99946

1,228 adverse event reports referencing this reaction

1,228
Total Reports
0
Deaths
0.0%
Death Rate

Species Most Affected

Unknown 1,212
Dog 11
Cat 3
Cattle 1
Human 1

Breeds Most Affected

Unknown 1,213
Dog (unknown) 3
Poodle - Miniature 2
Cat (other) 2
Retriever - Labrador 1
Shepherd Dog - German 1
Maltese 1
Terrier - Bull 1
Mixed (Cattle) 1
Greater Swiss Mountain Dog 1

Associated Drugs

Moxidectin 436
Cefovecin 131
Ivermectin + Pyrantel As Pamoate Salt 98
Propofol 98
Maropitant Citrate 60
Carprofen 33
Fluralaner 13.64% 12-Week Chew 23
Clindamycin Hydrochloride 20
Ceftiofur Sodium 19
Afoxolaner 14
Phenylpropropanolamine Hcl 12
Dexmedetomidine Hydrochloride 10
Selamectin;Sarolaner 10
Insulin Injectable Vial 8
Selamectin 8
Ketamine Hydrochloride 7
Oclacitinib Maleate 7
Butorphanol Tartrate 6
Ivermectin/Pyrantel Pamoate Chewable 34Mcg/81Mg 6
Melarsomine Dihydrochloride 6

Data Summary

Metric Value
Total reports referencing reaction 1,228
Reports with fatal outcome 0
Case-fatality rate (reported events) 0.0%
Species observed 5
Breeds observed 12
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 99946.

Contamination, Foreign Object Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 1,228 adverse event reports that reference Contamination, Foreign Object as a reaction term, including 0 reports with a death outcome — a 0.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 99946, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Contamination, Foreign Object appears most frequently in reports for Unknown (1,212 reports), Dog (11 reports), Cat (3 reports) — with Unknown dominating at 1,212 entries. Within those species, the breeds most often named alongside this reaction are Unknown (1,213), Dog (unknown) (3), Poodle - Miniature (2). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Contamination, Foreign Object are Moxidectin (436 reports), Cefovecin (131 reports), Ivermectin + Pyrantel As Pamoate Salt (98 reports), Propofol (98 reports), with Moxidectin appearing alongside this reaction in 436 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial