Injection site hair loss

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VeDDRA Code: 74

293 adverse event reports referencing this reaction

293
Total Reports
3
Deaths
100.0%
Death Rate

Species Most Affected

Dog 150
Cat 92
Horse 34
Cattle 12
Goat 4
White tailed deer 1

Breeds Most Affected

Domestic Shorthair 62
Retriever - Labrador 19
Quarter Horse 13
Chihuahua 10
Terrier - Yorkshire 10
Terrier - Bull - American Pit 9
Crossbred Canine/dog 8
Thoroughbred 7
Cat (other) 7
Dog (unknown) 7

Associated Drugs

Carprofen 35
Frunevetmab 32
Cefovecin 30
Meloxicam 20
Polysulfated Glycosaminoglycan 19
Bedinvetmab 19
Rabies Vaccine, Killed Virus 18
Ceftiofur Crystalline Free Acid 16
Gabapentin 15
Moxidectin 14
Maropitant Citrate 12
Enrofloxacin 11
Robenacoxib 11
Prednisone 11
Tulathromycin 10
Milbemycin Oxime + Praziquantel 10
Melarsomine Dihydrochloride 9
Bordetella Bronchiseptica Vaccine, Avirulent Live Culture 9
Diphenhydramine 8
Praziquantel 7

Data Summary

Metric Value
Total reports referencing reaction 293
Reports with fatal outcome 3
Case-fatality rate (reported events) 100.0%
Species observed 6
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 74.

Injection site hair loss Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 293 adverse event reports that reference Injection site hair loss as a reaction term, including 3 reports with a death outcome — a 100.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 74, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Injection site hair loss appears most frequently in reports for Dog (150 reports), Cat (92 reports), Horse (34 reports) — with Dog dominating at 150 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (62), Retriever - Labrador (19), Quarter Horse (13). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Injection site hair loss are Carprofen (35 reports), Frunevetmab (32 reports), Cefovecin (30 reports), Meloxicam (20 reports), with Carprofen appearing alongside this reaction in 35 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial