Reaction profile

The FDA adverse-event record for hypoventilation

15 FDA adverse-event reports reference hypoventilation (VeDDRA 2058). See the species, breeds, and drugs most associated with it below.

15
reports citing this reaction
53.3%
death-coded share
Dog
most-affected species
Propofol
most-associated drug
Verify with FDA CVM →
15
Total Reports
8
Deaths
53.3%
Death Rate

Species Most Affected

Dog 12
Cat 3

Breeds Most Affected

Shepherd Dog - German 2
Mixed (Dog) 2
Domestic Shorthair 2
Poodle (unspecified) 1
Pekingese 1
Domestic Longhair 1
Terrier - Yorkshire 1
Crossbred Canine/dog 1
Pug 1
Retriever - Labrador 1

Associated Drugs

Propofol 3
Maropitant Citrate 3
Spinosad 2
Acepromazine 2
Dexmedetomidine 2
Atipamezole Hydrochloride 2
Dexamethasone Sodium Phosphate 2
Midazolam Hydrochloride 2
Dexmedetomidine Hydrochloride 2
Ketamine 2
Milbemycin Oxime + Spinosad 1
Tramadol 1
Prednisolone Trimeprazine Tartrate 1
Ivermectin 1
Isoflurane 1
Dexmedetomidine Hcl 1
Milbemycin Oxime, Lufenuron 1
Phenobarbital 1
Fluralaner Chew Tablets 1
Anti-Il31 Mab Mcs Lot #1283563 1

Hypoventilation Reaction Insights

15 reports name Hypoventilation; 8 recorded a death outcome (53.3% of reported events, not a population-level mortality rate). VeDDRA code: 2058.

By species: Dog (12 reports), Cat (3 reports). By breed: Shepherd Dog - German (2), Mixed (Dog) (2), Domestic Shorthair (2).

Most co-reported drugs: Propofol (3 reports), Maropitant Citrate (3 reports), Spinosad (2 reports), Acepromazine (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.