Reaction profile

The FDA adverse-event record for hypoventilation

Name: Hypoventilation - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

16 FDA reports name hypoventilation, a lower-volume reaction in the CVM extract (VeDDRA 2058). Plate stamps and neighbourhood peers follow.

#2275 of 2,481
by report volume (all reactions): 16
reports citing this reaction: 50.0%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Hypoventilation has 16 reports now versus 15 in that prior snapshot: 1 more (6.7%).

Report change: +1
Death-coded reports: +0
Death-coded share: −3.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Hypoventilation changes

FDA AER · VeDDRA plate

Code 2058 VOL-TRACE

VOL-TRACE · DEATH-HOT · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 16 reports
DEATH-HOT 50.0%
BOTTOM-DECILE #2275/2481
PHOTO-FINISH Abdominal transudate
SPECIES-DOG Dog · 13
DRUG-LEAD Propofol · 3
DESK-WIDE 13 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Abdominal transudate (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Hypoventilation

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Hypoventilation

Hypoventilation: high death-coded share in the FDA AER plate

Signature read: 16 reports place Hypoventilation in the lower third of FDA AER volume (#2275 of 2,481). Report volume is lower-third scale: 16 named reports in the openFDA extract. Death-coded share is upper-third: 8 of 16 reports (50.0% of named reports). Nearest volume peer: Abdominal transudate (±0 reports). Lead species Dog (13). Lead co-reported drug Propofol (3).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 13

Cat 3

Breeds Most Affected

Shepherd Dog - German 2

Mixed (Dog) 2

Domestic Shorthair 2

Poodle (unspecified) 1

Pekingese 1

Domestic Longhair 1

Terrier - Yorkshire 1

Crossbred Canine/dog 1

Pug 1

Retriever - Labrador 1

Associated Drugs

Propofol 3

Atipamezole Hydrochloride 3

Maropitant Citrate 3

Dexmedetomidine Hydrochloride 3

Spinosad 2

Acepromazine 2

Dexmedetomidine 2

Dexamethasone Sodium Phosphate 2

Midazolam Hydrochloride 2

Ketamine 2

Milbemycin Oxime + Spinosad 1

Tramadol 1

Prednisolone Trimeprazine Tartrate 1

Ivermectin 1

Isoflurane 1

Milbemycin Oxime, Lufenuron 1

Dexmedetomidine Hcl 1

Phenobarbital 1

Fluralaner Chew Tablets 1

Anti-Il31 Mab Mcs Lot #1283563 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Hypoventilation (#2275 of 2,481 by report volume); death-coded 50.0%. PlainBreed reaction plate · report volume stamp 16 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →