Temporary blindness

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VeDDRA Code: 1829

440 adverse event reports referencing this reaction

440
Total Reports
33
Deaths
750.0%
Death Rate

Species Most Affected

Dog 331
Cat 74
Cattle 23
Horse 7
Human 4
Other Deer 1

Breeds Most Affected

Retriever - Labrador 29
Crossbred Canine/dog 27
Domestic Shorthair 22
Chihuahua 20
Domestic (unspecified) 19
Terrier - Yorkshire 17
Holstein-Friesian also known as Holstein 17
Shepherd Dog - German 16
Pit Bull 11
Bulldog 11

Associated Drugs

Ivermectin 89
Milbemycin Oxime + Spinosad 83
Spinosad 68
Ceftiofur Crystalline Free Acid 11
Fluralaner Chew Tablets 11
Orbifloxacin 10
Carprofen 9
Afoxolaner 9
Eprinomectin 8
Butorphanol 8
Buprenorphine 8
Dexmedetomidine 8
Pyrantel Pamoate;Sarolaner 8
Trilostane 7
Ceftiofur Hydrochloride 7
Isoflurane 7
Cefovecin 7
Sarolaner 7
Atipamezole 6
Selamectin 6

Data Summary

Metric Value
Total reports referencing reaction 440
Reports with fatal outcome 33
Case-fatality rate (reported events) 750.0%
Species observed 6
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1829.

Temporary blindness Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 440 adverse event reports that reference Temporary blindness as a reaction term, including 33 reports with a death outcome — a 750.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1829, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Temporary blindness appears most frequently in reports for Dog (331 reports), Cat (74 reports), Cattle (23 reports) — with Dog dominating at 331 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (29), Crossbred Canine/dog (27), Domestic Shorthair (22). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Temporary blindness are Ivermectin (89 reports), Milbemycin Oxime + Spinosad (83 reports), Spinosad (68 reports), Ceftiofur Crystalline Free Acid (11 reports), with Ivermectin appearing alongside this reaction in 89 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial