Reaction profile

The FDA adverse-event record for muscle tremor

2,279 FDA reports name muscle tremor, a high-volume reaction in the CVM extract (VeDDRA 684). Plate stamps and neighbourhood peers follow.

#202 of 2,481
by report volume (all reactions)
2,279
reports citing this reaction
10.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Muscle tremor has 2,279 reports now versus 2,259 in that prior snapshot: 20 more (0.9%).

Report change
+20
Death-coded reports
+1
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Muscle tremor changes

FDA AER · VeDDRA plate

Code 684 VOL-MID

VOL-MID · DEATH-PAR · TOP-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 2,279 reports
  • DEATH-PAR 10.0%
  • TOP-DECILE #202/2481
  • PHOTO-FINISH Containers, Abnormal
  • SPECIES-DOG Dog · 1,693
  • DRUG-LEAD Imidacloprid + Mo… · 338
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Containers, Abnormal (±2 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Muscle tremor

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Muscle tremor · this reaction2279Containers, Abnormal · near2277Anaphylactoid reaction · near2272Confusion · near2259Stumbling gait · near2252Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Muscle tremor

What the FDA AER plate says about Muscle tremor

Signature read: 2,279 reports place Muscle tremor in the upper third of FDA AER volume (#202 of 2,481). Report volume is upper-third scale: 2,279 named reports in the openFDA extract. 227 of 2,279 reports were death-coded (10.0% of named reports, not a population mortality rate). Nearest volume peer: Containers, Abnormal (±2 reports). Lead species Dog (1,693). Lead co-reported drug Imidacloprid + Moxidectin (338).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Imidacloprid + Moxidectin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 1,693
Cat 509
Horse 50
Cattle 9
Pig 7
Other Birds 2
Donkey 2
Mouse 1
Human 1
Ferret 1

Breeds Most Affected

Domestic Shorthair 359
Retriever - Labrador 156
Chihuahua 103
Crossbred Canine/dog 102
Terrier - Yorkshire 97
Shih Tzu 60
Maltese 57
Retriever - Golden 55
Boxer (German Boxer) 52
Dachshund (unspecified) 47

Associated Drugs

Imidacloprid + Moxidectin 338
Milbemycin Oxime + Spinosad 271
Sarolaner 196
Selamectin 138
Emodepside + Praziquantel 122
Pyrantel Pamoate;Sarolaner 122
Afoxolaner 98
Spinosad 85
Maropitant Citrate 79
Trilostane 60
Ivermectin 58
Fluralaner 13.64% 12-Week Chew 55
Carprofen 53
Fluralaner Chew Tablets 52
Moxidectin 51
Cefovecin 39
Gabapentin 39
Ivermectin + Pyrantel As Pamoate Salt 38
Bedinvetmab 38
Lotilaner 37

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Muscle tremor, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (2,279 here).

Similar death-coded share

Nearest other reactions by death-coded share (10.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Muscle tremor (#202 of 2,481 by report volume); death-coded 10.0%. PlainBreed reaction plate · report volume stamp 2,279 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →