Reaction profile

The FDA adverse-event record for droopy lower lip

87 FDA adverse-event reports reference droopy lower lip (VeDDRA 2454). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1458 of 2,481
by report volume (all reactions)
87
reports citing this reaction
8.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Droopy lower lip has 87 reports now versus 84 in that prior snapshot: 3 more (3.6%).

Report change
+3
Death-coded reports
+1
Death-coded share
+0.9 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Droopy lower lip changes

FDA AER · VeDDRA plate

Code 2454 VOL-LOW

VOL-LOW · DEATH-PAR · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 87 reports
  • DEATH-PAR 8.0%
  • MID-PACK #1458/2481
  • PHOTO-FINISH Bone marrow disorder…
  • SPECIES-DOG Dog · 78
  • DRUG-LEAD Trilostane · 16
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Bone marrow disorder NOS (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Droopy lower lip

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Bone marrow disorder… · near87Droopy lower lip · this reac…87INEFFECTIVE, LUNGWORMS · near87Localised numbness (s… · near87Low ionized calcium (… · near87Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Droopy lower lip

Droopy lower lip: low death-coded share in the FDA AER plate

Signature read: 7 death-coded reports is a thin tail count for Droopy lower lip in the CVM extract. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 7 of 87 reports (8.0% of named reports). Nearest volume peer: Bone marrow disorder NOS (±0 reports). Lead species Dog (78). Lead co-reported drug Trilostane (16).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Trilostane appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 78
Horse 7
Cat 2

Breeds Most Affected

Beagle 8
Shepherd Dog - German 7
Retriever - Labrador 6
Terrier - Bull - American Pit 4
Retriever - Golden 4
Crossbred Canine/dog 4
Pit Bull 4
Quarter Horse 3
Spaniel - Cocker American 3
Boxer (German Boxer) 3

Associated Drugs

Trilostane 16
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 15
Bedinvetmab 13
Afoxolaner 6
Carprofen 6
Pyrantel Pamoate;Sarolaner 6
Milbemycin Oxime + Spinosad 5
Fluralaner Chew Tablets 5
Ear Cleaner 5
Prednisone 5
Oclacitinib Maleate 4
Fish Oil 4
Maropitant Citrate 4
Gabapentin 4
Florfenicol, Terbinafine, Betamethasone Acetate 4
Cyclosporine 4
Ketoconazole 4
Marbofloxacin 3
Deracoxib 3
Ear Cleaner (Unknown) 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Droopy lower lip, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Droopy lower lip (#1458 of 2,481 by report volume); death-coded 8.0%. PlainBreed reaction plate · death-coded report count stamp 7 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →