Reaction profile

The FDA adverse-event record for blood in trachea

47 FDA adverse-event reports reference blood in trachea (VeDDRA 878). See the species, breeds, and drugs most associated with it below.

47
reports citing this reaction
70.2%
death-coded share
Dog
most-affected species
Dexmedetomidine Hydrochloride
most-associated drug
Verify with FDA CVM →
47
Total Reports
33
Deaths
70.2%
Death Rate

Species Most Affected

Dog 32
Cat 9
Cattle 5
Horse 1

Breeds Most Affected

Domestic Shorthair 6
Shiba Inu 2
Retriever - Golden 2
Chihuahua 2
Bulldog 2
Pug 2
Cat (unknown) 2
Shepherd Dog - German 2
Shepherd Dog - Australian 1
Collie - Border 1

Associated Drugs

Dexmedetomidine Hydrochloride 9
Isoflurane 5
Butorphanol 5
Cefovecin 4
Ivermectin + Pyrantel As Pamoate Salt 4
Milbemycin Oxime + Spinosad 3
Ketamine 3
Atipamezole Hydrochloride 3
Propofol 3
Dexmedetomidine 3
Carprofen 3
Cefazolin 2
Prednisone 2
Spinosad 2
Diphenhydramine 2
Butorphanol Tartrate 2
Buprenorphine 2
Afoxolaner 2
Melarsomine Dihydrochloride Injection 2
Ceftiofur Crystalline Free Acid 2

Blood in trachea Reaction Insights

47 reports name Blood in trachea; 33 recorded a death outcome (70.2% of reported events, not a population-level mortality rate). VeDDRA code: 878.

By species: Dog (32 reports), Cat (9 reports), Cattle (5 reports). By breed: Domestic Shorthair (6), Shiba Inu (2), Retriever - Golden (2).

Most co-reported drugs: Dexmedetomidine Hydrochloride (9 reports), Isoflurane (5 reports), Butorphanol (5 reports), Cefovecin (4 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.