Reaction profile

The FDA adverse-event record for digestive tract haemorrhage nos

199 FDA adverse-event reports reference digestive tract haemorrhage nos (VeDDRA 306). See the species, breeds, and drugs most associated with it below.

199
reports citing this reaction
53.8%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
199
Total Reports
107
Deaths
53.8%
Death Rate

Species Most Affected

Dog 166
Cat 12
Cattle 8
Horse 6
Pig 3
Chicken 2
Human 1
Rabbit 1

Breeds Most Affected

Retriever - Labrador 21
Dog (unknown) 17
Crossbred Canine/dog 11
Retriever - Golden 9
Dachshund (unspecified) 7
Boxer (German Boxer) 6
Terrier - Yorkshire 6
Chihuahua 5
Mixed (Dog) 5
Pug 5

Associated Drugs

Carprofen 37
Milbemycin Oxime + Spinosad 23
Maropitant Citrate 17
Meloxicam 12
Deracoxib 12
Moxidectin 11
Polysulfated Glycosaminoglycan 10
Trilostane 10
Oclacitinib Maleate 9
Firocoxib 8
Prednisone 7
Gabapentin 7
Sucralfate 6
Fluralaner 13.64% 12-Week Chew 6
Bedinvetmab 6
Spinosad 5
Monensin Sodium 5
Buprenorphine 5
Famotidine 5
Enrofloxacin 5

Digestive tract haemorrhage NOS Reaction Insights

199 reports name Digestive tract haemorrhage NOS; 107 recorded a death outcome (53.8% of reported events, not a population-level mortality rate). VeDDRA code: 306.

By species: Dog (166 reports), Cat (12 reports), Cattle (8 reports). By breed: Retriever - Labrador (21), Dog (unknown) (17), Crossbred Canine/dog (11).

Most co-reported drugs: Carprofen (37 reports), Milbemycin Oxime + Spinosad (23 reports), Maropitant Citrate (17 reports), Meloxicam (12 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.