Stupor

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VeDDRA Code: 1019

635 adverse event reports referencing this reaction

635
Total Reports
182
Deaths
2870.0%
Death Rate

Species Most Affected

Dog 477
Cat 141
Horse 9
Human 3
Cattle 3
Donkey 1
Rabbit 1

Breeds Most Affected

Domestic (unspecified) 66
Crossbred Canine/dog 55
Retriever - Labrador 45
Boxer (German Boxer) 26
Domestic Shorthair 24
Chihuahua 21
Terrier - Yorkshire 19
Retriever - Golden 19
Cat (unknown) 16
Shepherd Dog - German 13

Associated Drugs

Spinosad 70
Milbemycin Oxime + Spinosad 70
Carprofen 36
Meloxicam 32
Maropitant Citrate 28
Ivermectin 24
Deracoxib 19
Dexmedetomidine Hydrochloride 17
Afoxolaner 17
Selamectin 16
Buprenorphine 16
Ivermectin, Pyrantel 15
Cefovecin Sodium 12
Cefovecin 12
Trilostane 11
Human Insulin 10
Cyclosporine 10
Butorphanol Tartrate 10
Maropitant 10
Ivermectin + Pyrantel As Pamoate Salt 10

Data Summary

Metric Value
Total reports referencing reaction 635
Reports with fatal outcome 182
Case-fatality rate (reported events) 2870.0%
Species observed 7
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1019.

Stupor Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 635 adverse event reports that reference Stupor as a reaction term, including 182 reports with a death outcome — a 2870.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1019, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Stupor appears most frequently in reports for Dog (477 reports), Cat (141 reports), Horse (9 reports) — with Dog dominating at 477 entries. Within those species, the breeds most often named alongside this reaction are Domestic (unspecified) (66), Crossbred Canine/dog (55), Retriever - Labrador (45). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Stupor are Spinosad (70 reports), Milbemycin Oxime + Spinosad (70 reports), Carprofen (36 reports), Meloxicam (32 reports), with Spinosad appearing alongside this reaction in 70 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial