Reaction profile

The FDA adverse-event record for stupor

640 FDA reports name stupor, a high-volume reaction in the CVM extract (VeDDRA 1019). Plate stamps and neighbourhood peers follow.

#550 of 2,481
by report volume (all reactions)
640
reports citing this reaction
28.9%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Stupor has 640 reports now versus 638 in that prior snapshot: 2 more (0.3%).

Report change
+2
Death-coded reports
+1
Death-coded share
+0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Stupor changes

FDA AER · VeDDRA plate

Code 1019 VOL-MID

VOL-MID · DEATH-HOT · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 640 reports
  • DEATH-HOT 28.9%
  • UPPER-Q #550/2481
  • PHOTO-FINISH Pyrexia
  • SPECIES-DOG Dog · 478
  • DRUG-LEAD Spinosad · 70
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Pyrexia (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Stupor

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Urinary bladder disor… · near641Pyrexia · near640Pyuria · near640Stupor · this reaction640Partial anorexia · near638Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Stupor

Stupor: high death-coded share in the FDA AER plate

Signature read: 185 death-coded reports is a heavy tail count for Stupor in the CVM extract. Report volume is upper-third scale: 640 named reports in the openFDA extract. Death-coded share is upper-third: 185 of 640 reports (28.9% of named reports). Nearest volume peer: Pyrexia (±0 reports). Lead species Dog (478). Lead co-reported drug Spinosad (70).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 478
Cat 145
Horse 9
Human 3
Cattle 3
Donkey 1
Rabbit 1

Breeds Most Affected

Domestic (unspecified) 66
Crossbred Canine/dog 55
Retriever - Labrador 45
Domestic Shorthair 27
Boxer (German Boxer) 26
Chihuahua 21
Terrier - Yorkshire 19
Retriever - Golden 19
Cat (unknown) 16
Shepherd Dog - German 13

Associated Drugs

Spinosad 70
Milbemycin Oxime + Spinosad 70
Carprofen 36
Meloxicam 32
Maropitant Citrate 28
Ivermectin 24
Deracoxib 19
Dexmedetomidine Hydrochloride 17
Afoxolaner 17
Selamectin 16
Buprenorphine 16
Ivermectin, Pyrantel 15
Cefovecin Sodium 12
Cefovecin 12
Trilostane 11
Maropitant 10
Human Insulin 10
Butorphanol Tartrate 10
Cyclosporine 10
Ivermectin + Pyrantel As Pamoate Salt 10

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Stupor, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (640 here).

Similar death-coded share

Nearest other reactions by death-coded share (28.9% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Stupor (#550 of 2,481 by report volume); death-coded 28.9%. PlainBreed reaction plate · death-coded report count stamp 185 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →