Reaction profile

The FDA adverse-event record for stupor

635 FDA adverse-event reports reference stupor (VeDDRA 1019). See the species, breeds, and drugs most associated with it below.

635
reports citing this reaction
28.7%
death-coded share
Dog
most-affected species
Spinosad
most-associated drug
Verify with FDA CVM →
635
Total Reports
182
Deaths
28.7%
Death Rate

Species Most Affected

Dog 477
Cat 141
Horse 9
Human 3
Cattle 3
Donkey 1
Rabbit 1

Breeds Most Affected

Domestic (unspecified) 66
Crossbred Canine/dog 55
Retriever - Labrador 45
Boxer (German Boxer) 26
Domestic Shorthair 24
Chihuahua 21
Terrier - Yorkshire 19
Retriever - Golden 19
Cat (unknown) 16
Shepherd Dog - German 13

Associated Drugs

Spinosad 70
Milbemycin Oxime + Spinosad 70
Carprofen 36
Meloxicam 32
Maropitant Citrate 28
Ivermectin 24
Deracoxib 19
Dexmedetomidine Hydrochloride 17
Afoxolaner 17
Selamectin 16
Buprenorphine 16
Ivermectin, Pyrantel 15
Cefovecin Sodium 12
Cefovecin 12
Trilostane 11
Human Insulin 10
Cyclosporine 10
Butorphanol Tartrate 10
Maropitant 10
Ivermectin + Pyrantel As Pamoate Salt 10

Stupor Reaction Insights

635 reports name Stupor; 182 recorded a death outcome (28.7% of reported events, not a population-level mortality rate). VeDDRA code: 1019.

By species: Dog (477 reports), Cat (141 reports), Horse (9 reports). By breed: Domestic (unspecified) (66), Crossbred Canine/dog (55), Retriever - Labrador (45).

Most co-reported drugs: Spinosad (70 reports), Milbemycin Oxime + Spinosad (70 reports), Carprofen (36 reports), Meloxicam (32 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.