Reaction profile

The FDA adverse-event record for caps, abnormal

2,207 FDA adverse-event reports reference caps, abnormal (VeDDRA 99002). See the species, breeds, and drugs most associated with it below.

2,207
reports citing this reaction
0.1%
death-coded share
Unknown
most-affected species
Selamectin
most-associated drug
Verify with FDA CVM →
2,207
Total Reports
2
Deaths
0.1%
Death Rate

Species Most Affected

Unknown 2,136
Human 51
Cat 11
Dog 8
Cattle 1

Breeds Most Affected

Unknown 2,188
Domestic Shorthair 5
Cat (unknown) 3
Cat (other) 2
Domestic (unspecified) 1
Sheepdog - Polish Lowland 1
Retriever - Labrador 1
Poodle - Toy 1
Chihuahua 1
Holstein-Friesian also known as Holstein 1

Associated Drugs

Selamectin 329
Selamectin;Sarolaner 279
Doramectin 242
Meloxicam 171
Ivermectin(1%)/Clorsulon(10%) Injection 98
Cyclosporine 79
Moxidectin 65
Fluralaner Spot-On Solution 60
Pimobendan 56
Ivermectin 35
Tresaderm Dermatological Solution 34
Imidacloprid + Moxidectin 31
Enrofloxacin 25
Eprinomectin 5 Mg/Ml Pour-On Solution 24
Carprofen 22
Metronidazole 22
Dirlotapide 19
Firocoxib 15
Eprinomectin 15
Equipment 14

Caps, Abnormal Reaction Insights

2,207 reports name Caps, Abnormal; 2 recorded a death outcome (0.1% of reported events, not a population-level mortality rate). VeDDRA code: 99002.

By species: Unknown (2,136 reports), Human (51 reports), Cat (11 reports). By breed: Unknown (2,188), Domestic Shorthair (5), Cat (unknown) (3).

Most co-reported drugs: Selamectin (329 reports), Selamectin;Sarolaner (279 reports), Doramectin (242 reports), Meloxicam (171 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.