Reaction profile

The FDA adverse-event record for localised allergic oedema nos

18 FDA reports name localised allergic oedema nos, a lower-volume reaction in the CVM extract (VeDDRA 2767). Plate stamps and neighbourhood peers follow.

#2218 of 2,481
by report volume (all reactions)
18
reports citing this reaction
5.6%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Localised allergic oedema NOS has 18 reports now versus 15 in that prior snapshot: 3 more (20.0%).

Report change
+3
Death-coded reports
+1
Death-coded share
+5.6 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Localised allergic oedema NOS changes

FDA AER · VeDDRA plate

Code 2767 VOL-TRACE

VOL-TRACE · DEATH-PAR · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 18 reports
  • DEATH-PAR 5.6%
  • LOWER-Q #2218/2481
  • PHOTO-FINISH ALBUMIN/GLOBULIN RATI…
  • SPECIES-DOG Dog · 14
  • DRUG-LEAD Moxidectin · 5
  • DESK-WIDE 12 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: ALBUMIN/GLOBULIN RATIO HI, BLD (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Localised allergic oedema NOS

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348ALBUMIN/GLOBULIN RATI… · near18Application site skin… · near18Bone marrow hypoplasia · near18Cognitive disturbance · near18Localised allergic oe… · thi…18Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Localised allergic oedema NOS

Localised allergic oedema NOS: low death-coded share in the FDA AER plate

Signature read: 18 reports place Localised allergic oedema NOS in the lower third of FDA AER volume (#2218 of 2,481). Report volume is lower-third scale: 18 named reports in the openFDA extract. Death-coded share is lower-third: 1 of 18 reports (5.6% of named reports). Nearest volume peer: ALBUMIN/GLOBULIN RATIO HI, BLD (±0 reports). Lead species Dog (14). Lead co-reported drug Moxidectin (5).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Moxidectin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 14
Cat 3
Human 1

Breeds Most Affected

Chihuahua 2
Beagle 2
Terrier - Bull - American Pit 2
Ragdoll 2
Retriever - Golden 2
Poodle (unspecified) 2
Pug 1
Unknown 1
Crossbred Canine/dog 1
Hound - Basset 1

Associated Drugs

Moxidectin 5
Propofol 3
Maropitant Citrate 3
Rabies Virus, Kv 3
Anti-Il31 Mab Mcs Lot #1283563 3
Meloxicam 3
Tigilanol Tiglate 2
Carprofen 2
Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim 2
Lidocaine 2
Hydromorphone 2
Sevoflurane 2
Amoxicillin Trihydrate;Clavulanate Potassium ( K-Clavulanate) 2
Rabies Vaccine 2
Pimobendan 2
Taurine 2
Nitenpyram 1
Methadone 1
Dexmedetomidine Hydrochloride 1
Midazolam 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Localised allergic oedema NOS (#2218 of 2,481 by report volume); death-coded 5.6%. PlainBreed reaction plate · report volume stamp 18 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →