Reaction profile

The FDA adverse-event record for respiratory failure

49 FDA reports name respiratory failure, a lower-volume reaction in the CVM extract (VeDDRA 1167). Plate stamps and neighbourhood peers follow.

#1748 of 2,481
by report volume (all reactions)
49
reports citing this reaction
85.7%
death-coded share
Dog
most-affected species
Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Respiratory failure has 49 reports now versus 47 in that prior snapshot: 2 more (4.3%).

Report change
+2
Death-coded reports
+1
Death-coded share
−1.5 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Respiratory failure changes

FDA AER · VeDDRA plate

Code 1167 VOL-TRACE

VOL-TRACE · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 49 reports
  • DEATH-HOT 85.7%
  • MID-PACK #1748/2481
  • PHOTO-FINISH Entropion
  • SPECIES-DOG Dog · 35
  • DRUG-LEAD Moxidectin · 6
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Entropion (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Respiratory failure

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Entropion · near49Hepatic fibrosis · near49INEFFECTIVE, STRONGYL… · near49Nerve damage NOS · near49Respiratory failure · this r…49Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Respiratory failure

Respiratory failure: high death-coded share in the FDA AER plate

Signature read: Respiratory failure's 85.7% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 49 named reports in the openFDA extract. Death-coded share is upper-third: 42 of 49 reports (85.7% of named reports). Nearest volume peer: Entropion (±0 reports). Lead species Dog (35). Lead co-reported drug Moxidectin (6).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 35
Cat 12
Cattle 2

Breeds Most Affected

Domestic Shorthair 7
Shih Tzu 3
Holstein-Friesian also known as Holstein 2
Bulldog 2
Dog (unknown) 2
Chihuahua 2
Dachshund (unspecified) 2
Maltese 2
Terrier - Bull - American Pit 2
Cat (other) 2

Associated Drugs

Moxidectin 6
Spinosad 5
Metronidazole 5
Buprenorphine 5
Melarsomine Dihydrochloride 4
Milbemycin Oxime + Spinosad 3
Pyrantel Pamoate 3
Meloxicam 3
Butorphanol 3
Isoflurane 3
Maropitant Citrate 3
Metoclopramide 3
Maropitant 3
Dexamethasone 2
Carprofen 2
Doxycycline 2
Famotidine 2
Nitenpyram 2
Methylprednisolone Acetate 2
Atropine 2

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Respiratory failure (#1748 of 2,481 by report volume); death-coded 85.7%. PlainBreed reaction plate · death-coded share stamp 85.7% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →