Reaction profile

The FDA adverse-event record for disorder of red blood cell nos

383 FDA reports name disorder of red blood cell nos, a high-volume reaction in the CVM extract (VeDDRA 1416). Plate stamps and neighbourhood peers follow.

#750 of 2,481
by report volume (all reactions)
383
reports citing this reaction
21.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Disorder of red blood cell NOS has 383 reports now versus 373 in that prior snapshot: 10 more (2.7%).

Report change
+10
Death-coded reports
+0
Death-coded share
−0.6 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Disorder of red blood cell NOS changes

FDA AER · VeDDRA plate

Code 1416 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 383 reports
  • DEATH-HOT 21.1%
  • MID-PACK #750/2481
  • PHOTO-FINISH Physical label missing
  • SPECIES-DOG Dog · 344
  • DRUG-LEAD Milbemycin Oxime… · 79
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Physical label missing (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Disorder of red blood cell NOS

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Petechiae NOS · near384Disorder of red blood… · thi…383Physical label missing · near383Hair modification NOS · near382Proprioception loss · near382Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Disorder of red blood cell NOS

What the FDA AER plate says about Disorder of red blood cell NOS

Signature read: 81 death-coded reports is a heavy tail count for Disorder of red blood cell NOS in the CVM extract. Report volume is upper-third scale: 383 named reports in the openFDA extract. 81 of 383 reports were death-coded (21.1% of named reports, not a population mortality rate). Nearest volume peer: Physical label missing (±0 reports). Lead species Dog (344). Lead co-reported drug Milbemycin Oxime + Spinosad (79).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 344
Cat 37
Horse 2

Breeds Most Affected

Crossbred Canine/dog 36
Retriever - Labrador 32
Domestic Shorthair 23
Chihuahua 13
Boxer (German Boxer) 12
Terrier - Yorkshire 12
Shih Tzu 10
Terrier (unspecified) 10
Shepherd Dog - German 10
Retriever - Golden 10

Associated Drugs

Milbemycin Oxime + Spinosad 79
Carprofen 39
Trilostane 34
Fluralaner 13.64% 12-Week Chew 32
Maropitant Citrate 24
Oclacitinib Maleate 24
Spinosad 23
Fluralaner Chew Tablets 22
Moxidectin 18
Gabapentin 16
Famotidine 12
Doxycycline 12
Prednisone 12
Ivermectin 10
Cefovecin 10
Anti-Il31 Mab Mcs Lot #1283563 10
Afoxolaner 10
Selamectin 9
Rabies Vaccine 8
Metronidazole 8

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Disorder of red blood cell NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (383 here).

Similar death-coded share

Nearest other reactions by death-coded share (21.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Disorder of red blood cell NOS (#750 of 2,481 by report volume); death-coded 21.1%. PlainBreed reaction plate · death-coded report count stamp 81 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →