Reaction profile

The FDA adverse-event record for elevated c-reactive protein

12 FDA adverse-event reports reference elevated c-reactive protein (VeDDRA 2267). See the species, breeds, and drugs most associated with it below.

12
reports citing this reaction
8.3%
death-coded share
Dog
most-affected species
Robenacoxib
most-associated drug
Verify with FDA CVM →
12
Total Reports
1
Deaths
8.3%
Death Rate

Species Most Affected

Dog 12

Breeds Most Affected

Dog (unknown) 3
Dachshund - Miniature 2
Shih Tzu 1
Bulldog 1
Corgi - Welsh Cardigan 1
Terrier - Cairn 1
Crossbred Canine/dog 1
Mastiff (unspecified) 1
Siberian Husky 1

Associated Drugs

Robenacoxib 5
Firocoxib 57 Mg Chewable 2
Meloxicam 2
Oclacitinib Maleate 1
Hypoallergenic Diet 1
Adequan Canine 1
Afoxolaner 28.3 Mg Chewable Tablets 1
Afoxolaner 11.3 Mg Chewable Tablets 1
Afoxolaner 68 Mg Chewable Tablets 1
Fluralaner 13.64% 12-Week Chew 1
Afoxolaner 1
Deracoxib 1
Rabies Vaccine 1
Ketoconazole 1
Dexamethasone 1
Fluconazole 1
Milbemycin Oxime + Spinosad 1
Isoflurane 1
Ampicillin 1
Equipromazina 1

Elevated C-reactive protein Reaction Insights

12 reports name Elevated C-reactive protein; 1 recorded a death outcome (8.3% of reported events, not a population-level mortality rate). VeDDRA code: 2267.

By species: Dog (12 reports). By breed: Dog (unknown) (3), Dachshund - Miniature (2), Shih Tzu (1).

Most co-reported drugs: Robenacoxib (5 reports), Firocoxib 57 Mg Chewable (2 reports), Meloxicam (2 reports), Oclacitinib Maleate (1 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.