Reaction profile

The FDA adverse-event record for disseminated intravascular coagulation

189 FDA adverse-event reports reference disseminated intravascular coagulation (VeDDRA 154). See the species, breeds, and drugs most associated with it below.

189
reports citing this reaction
84.1%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
189
Total Reports
159
Deaths
84.1%
Death Rate

Species Most Affected

Dog 161
Cat 15
Horse 10
Cattle 1
Primate 1
Human 1

Breeds Most Affected

Retriever - Labrador 25
Crossbred Canine/dog 9
Retriever - Golden 9
Dachshund (unspecified) 7
Domestic Shorthair 7
Shepherd Dog - German 6
Chihuahua 5
Boxer (German Boxer) 5
Weimaraner 5
Dog (unknown) 4

Associated Drugs

Carprofen 19
Maropitant Citrate 18
Moxidectin 13
Meloxicam 12
Plasma 11
Milbemycin Oxime + Spinosad 11
Melarsomine Dihydrochloride 10
Deracoxib 10
Enrofloxacin 8
Prednisone 8
Diphenhydramine Hcl 8
Tramadol 7
Famotidine 7
Metronidazole 7
Spinosad 6
Fluralaner Chew Tablets 6
Firocoxib 5
Dexamethasone Sodium Phosphate 5
Cefovecin 5
Dexamethasone 5

Disseminated intravascular coagulation Reaction Insights

189 reports name Disseminated intravascular coagulation; 159 recorded a death outcome (84.1% of reported events, not a population-level mortality rate). VeDDRA code: 154.

By species: Dog (161 reports), Cat (15 reports), Horse (10 reports). By breed: Retriever - Labrador (25), Crossbred Canine/dog (9), Retriever - Golden (9).

Most co-reported drugs: Carprofen (19 reports), Maropitant Citrate (18 reports), Moxidectin (13 reports), Meloxicam (12 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.