Reaction profile

The FDA adverse-event record for disseminated intravascular coagulation

195 FDA adverse-event reports reference disseminated intravascular coagulation (VeDDRA 154). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1051 of 2,481
by report volume (all reactions)
195
reports citing this reaction
84.6%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Disseminated intravascular coagulation has 195 reports now versus 191 in that prior snapshot: 4 more (2.1%).

Report change
+4
Death-coded reports
+4
Death-coded share
+0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Disseminated intravascular coagulation changes

FDA AER · VeDDRA plate

Code 154 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 195 reports
  • DEATH-HOT 84.6%
  • MID-PACK #1051/2481
  • PHOTO-FINISH Alteration of milk qu…
  • SPECIES-DOG Dog · 166
  • DRUG-LEAD Carprofen · 22
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Alteration of milk quality (±1 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Disseminated intravascular coagulation

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Burning sensation of… · near196Localised skin reacti… · near196Disseminated intravas… · thi…195Alteration of milk qu… · near194Itchy rash · near194Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Disseminated intravascular coagulation

Disseminated intravascular coagulation: high death-coded share in the FDA AER plate

Signature read: Disseminated intravascular coagulation's 84.6% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 165 of 195 reports (84.6% of named reports). Nearest volume peer: Alteration of milk quality (±1 reports). Lead species Dog (166). Lead co-reported drug Carprofen (22).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 166
Cat 16
Horse 10
Cattle 1
Primate 1
Human 1

Breeds Most Affected

Retriever - Labrador 25
Crossbred Canine/dog 10
Retriever - Golden 9
Dachshund (unspecified) 8
Domestic Shorthair 8
Shepherd Dog - German 6
Chihuahua 5
Boxer (German Boxer) 5
Weimaraner 5
Dog (unknown) 4

Associated Drugs

Carprofen 22
Maropitant Citrate 20
Moxidectin 13
Meloxicam 12
Melarsomine Dihydrochloride 11
Plasma 11
Milbemycin Oxime + Spinosad 11
Deracoxib 10
Prednisone 9
Enrofloxacin 9
Metronidazole 9
Famotidine 8
Diphenhydramine Hcl 8
Tramadol 7
Cefovecin 7
Gabapentin 7
Spinosad 6
Fluralaner Chew Tablets 6
Maropitant 5
Firocoxib 5

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Disseminated intravascular coagulation, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (195 here).

Similar death-coded share

Nearest other reactions by death-coded share (84.6% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Disseminated intravascular coagulation (#1051 of 2,481 by report volume); death-coded 84.6%. PlainBreed reaction plate · death-coded share stamp 84.6% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →