Reaction profile

The FDA adverse-event record for proprioception deficit

1,865 FDA reports name proprioception deficit, a high-volume reaction in the CVM extract (VeDDRA 1157). Plate stamps and neighbourhood peers follow.

#246 of 2,481
by report volume (all reactions)
1,865
reports citing this reaction
23.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Proprioception deficit has 1,865 reports now versus 1,804 in that prior snapshot: 61 more (3.4%).

Report change
+61
Death-coded reports
+14
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Proprioception deficit changes

FDA AER · VeDDRA plate

Code 1157 VOL-MID

VOL-MID · DEATH-HOT · TOP-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 1,865 reports
  • DEATH-HOT 23.8%
  • TOP-DECILE #246/2481
  • PHOTO-FINISH Decreased activity
  • SPECIES-DOG Dog · 1,722
  • DRUG-LEAD Bedinvetmab · 765
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Decreased activity (±10 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Proprioception deficit

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Proprioception deficit · thi…1865Decreased activity · near1855Head tilt - ear disor… · near1848Localised pain NOS (s… · near1833Stiffness NOS · near1827Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Proprioception deficit

What the FDA AER plate says about Proprioception deficit

Signature read: 443 death-coded reports is a heavy tail count for Proprioception deficit in the CVM extract. Report volume is upper-third scale: 1,865 named reports in the openFDA extract. 443 of 1,865 reports were death-coded (23.8% of named reports, not a population mortality rate). Nearest volume peer: Decreased activity (±10 reports). Lead species Dog (1,722). Lead co-reported drug Bedinvetmab (765).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Bedinvetmab appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 1,722
Cat 122
Horse 12
Pig 4
Sheep 3
Rabbit 1
Cattle 1

Breeds Most Affected

Retriever - Labrador 275
Crossbred Canine/dog 109
Shepherd Dog - German 101
Domestic Shorthair 87
Retriever - Golden 77
Boxer (German Boxer) 56
Terrier - Bull - American Pit 52
Shih Tzu 44
Chihuahua 44
Terrier - Yorkshire 40

Associated Drugs

Bedinvetmab 765
Carprofen 295
Gabapentin 276
Milbemycin Oxime + Spinosad 133
Prednisone 88
Maropitant Citrate 86
Oclacitinib Maleate 78
Grapiprant 76
Pyrantel Pamoate;Sarolaner 75
Fluralaner Chew Tablets 71
Fluralaner 13.64% 12-Week Chew 67
Moxidectin 66
Sarolaner 57
Trilostane 56
Galliprant 53
Meloxicam 48
Afoxolaner 48
Spinosad 45
Polysulfated Glycosaminoglycan 44
Cefovecin 43

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Proprioception deficit, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (23.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Proprioception deficit (#246 of 2,481 by report volume); death-coded 23.8%. PlainBreed reaction plate · death-coded report count stamp 443 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →