Reaction profile

The FDA adverse-event record for proprioception deficit

1,705 FDA adverse-event reports reference proprioception deficit (VeDDRA 1157). See the species, breeds, and drugs most associated with it below.

1,705
reports citing this reaction
23.3%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
1,705
Total Reports
398
Deaths
23.3%
Death Rate

Species Most Affected

Dog 1,581
Cat 106
Horse 9
Pig 4
Sheep 3
Rabbit 1
Cattle 1

Breeds Most Affected

Retriever - Labrador 253
Crossbred Canine/dog 99
Shepherd Dog - German 88
Domestic Shorthair 75
Retriever - Golden 70
Boxer (German Boxer) 54
Terrier - Bull - American Pit 46
Chihuahua 42
Shih Tzu 40
Terrier - Yorkshire 39

Associated Drugs

Bedinvetmab 650
Carprofen 260
Gabapentin 233
Milbemycin Oxime + Spinosad 132
Prednisone 82
Maropitant Citrate 81
Oclacitinib Maleate 72
Fluralaner Chew Tablets 71
Pyrantel Pamoate;Sarolaner 67
Grapiprant 66
Fluralaner 13.64% 12-Week Chew 63
Moxidectin 61
Sarolaner 56
Trilostane 53
Galliprant 52
Afoxolaner 46
Spinosad 45
Meloxicam 43
Cefovecin 42
Tramadol 38

Proprioception deficit Reaction Insights

1,705 reports name Proprioception deficit; 398 recorded a death outcome (23.3% of reported events, not a population-level mortality rate). VeDDRA code: 1157.

By species: Dog (1,581 reports), Cat (106 reports), Horse (9 reports). By breed: Retriever - Labrador (253), Crossbred Canine/dog (99), Shepherd Dog - German (88).

Most co-reported drugs: Bedinvetmab (650 reports), Carprofen (260 reports), Gabapentin (233 reports), Milbemycin Oxime + Spinosad (132 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.